An ethical analysis of therapy for severe congenital kidney and urinary tract anomalies

D Claes, KB Markham, DME Cortezzo - Pediatrics, 2024 - publications.aap.org
Technological advancements before and after delivery have greatly altered the counseling
of pregnant patients facing a fetal diagnosis of severe oligohydramnios or anhydramnios …

Congenital urinary tract obstruction

KW Cheung, RK Morris, MD Kilby - Best Practice & Research Clinical …, 2019 - Elsevier
Congenital bladder neck obstruction (or lower urinary tract obstruction [LUTO]) describes a
heterogeneous group of congenital anomalies presenting with similar prenatal …

Neonatal survival after serial amnioinfusions for bilateral renal agenesis: the renal anhydramnios fetal therapy trial

JL Miller, AA Baschat, M Rosner, YJ Blumenfeld… - JAMA, 2023 - jamanetwork.com
Importance Early anhydramnios during pregnancy, resulting from fetal bilateral renal
agenesis, causes lethal pulmonary hypoplasia in neonates. Restoring amniotic fluid via …

Design and protocol of the renal anhydramnios fetal therapy (RAFT) trial

MA Atkinson, EB Jelin, A Baschat, YJ Blumenfeld… - Clinical …, 2022 - Elsevier
Purpose Anhydramnios secondary to anuria before 22 weeks of gestational age and
congenital bilateral renal agenesis before 26 weeks of gestational age are collectively …

Amnioinfusions to treat early onset anhydramnios caused by renal anomalies: background and rationale for the renal anhydramnios fetal therapy trial

EM O'Hare, AC Jelin, JL Miller, R Ruano… - Fetal diagnosis and …, 2019 - karger.com
Anhydramnios caused by early anuria is thought to be universally fatal due to pulmonary
hypoplasia. Bilateral renal agenesis and early fetal renal failure leading to anhydramnios …

Fetal surgery

HD Baumgarten, AW Flake - Pediatric Clinics, 2019 - pediatric.theclinics.com
Fetal surgery is an established but still rapidly evolving specialty, born from the rationale that
destructive embryologic processes, recognized early in gestation, can be curtailed by …

[PDF][PDF] Fetal therapy for renal anhydramnios

JL Miller, AA Baschat, MA Atkinson - Clinics in Perinatology, 2022 - Elsevier
The most severe forms of congenital anomalies of the kidney and urinary tract present in
fetal life with early pregnancy renal anhydramnios and are considered lethal due to …

Application of the human amniotic membrane as an adjuvant therapy for the treatment of hepatocellular carcinoma

AM Abou-Shanab, OA Gaser, RA Salah, N El-Badri - 2023 - Springer
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related morbidity
and mortality worldwide. Current therapeutic approaches suffer significant side effects and …

Pulmonary hypoplasia correlates with the length of anhydramnios in patients with early pregnancy renal anhydramnios (EPRA)

EB Jelin, JE Hooper, E Duregon, AK Williamson… - Journal of …, 2021 - nature.com
Background Early pregnancy renal anhydramanios (EPRA) occurs when the fetus is anuric
before 22 weeks gestational age (GA) and is considered universally lethal. Serial …

Renal agenesis

A Jelin… - American Journal of …, 2021 - Elsevier
Renal agenesis occurs when the ureteric bud fails to fuse with the metanephric blastema
during embryogenesis, resulting in the absence of the nephron and often the ureter …