La was first identified as a polypeptide component of ribonucleic protein complexes targeted
by antibodies in autoimmune patients and is now known to be a eukaryote cell‐ubiquitous …

Notable progress has been made in the therapeutic and research applications of cyclic
peptides since our previous review. New drugs based on cyclic peptides are entering the …

In the design and development of therapeutic agents, macromolecules with restricted
structures have stronger competitive edges than linear biological entities since cyclization …

Peptides and peptide-based materials have an increasing role in the treatment of viral
infections through their use as active pharmaceutical ingredients, targeting moieties …

Being able to effectively target RNA with potent ligands will open up a large number of
potential therapeutic options. The knowledge on how to achieve this is ever expanding but …

DNA and RNA play pivotal roles in life processes by storing and transferring genetic
information, modulating gene expression, and contributing to essential cellular machinery …

A RNAi based antiviral strategy holds the promise to impede hepatitis C viral (HCV) infection
overcoming the problem of emergence of drug resistant variants, usually encountered in the …

Epitranscriptomics is the study of global modification patterns to both coding and noncoding
RNA. Understanding the epitranscriptomic profile of disease states or individual patients is …

RNA provides the genetic blueprint for many pathogenic viruses, including SARS-CoV-2.
The propensity of RNA to fold into specific tertiary structures enables the biomolecular …

Human La protein is known to be an essential host factor for translation and replication of
hepatitis C virus (HCV) RNA. Previously, we have demonstrated that residues responsible …