Novel variant of thyroglobulin promoter triggers thyroid autoimmunity through an epigenetic interferon α-modulated mechanism
M Stefan, EM Jacobson, AK Huber… - Journal of Biological …, 2011 - ASBMB
Autoimmune thyroid diseases (AITD) arise from complex interactions between genetic,
epigenetic, and environmental factors. Whole genome linkage scans and association …
epigenetic, and environmental factors. Whole genome linkage scans and association …
The genetic basis of graves' disease
R Ploski, K Szymanski, T Bednarczuk - Current genomics, 2011 - ingentaconnect.com
The presented comprehensive review of current knowledge about genetic factors
predisposing to Graves' disease (GD) put emphasis on functional significance of observed …
predisposing to Graves' disease (GD) put emphasis on functional significance of observed …
Diagnostic value of antithyroid peroxidase antibody for incidental autoimmune thyroiditis based on histopathologic results
MH Rho, DW Kim, HP Hong, YM Park, MJ Kwon… - Endocrine, 2012 - Springer
Detection of antithyroid peroxidase antibody (TPOAb) is widely used in the diagnosis of
autoimmune thyroiditis (AIT), but no research has evaluated the diagnostic accuracy of …
autoimmune thyroiditis (AIT), but no research has evaluated the diagnostic accuracy of …
Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?
K Lacka, A Maciejewski, P Jarecki, W Herman… - International Journal of …, 2024 - mdpi.com
(1) Autoimmune thyroiditis (AIT) is the most common cause of primary hypothyroidism and
one of the most frequent organ-specific autoimmune diseases. Its pathogenesis is polygenic …
one of the most frequent organ-specific autoimmune diseases. Its pathogenesis is polygenic …
A novel mouse model of autoimmune thyroiditis induced by immunization with adenovirus containing full-length thyroglobulin cDNA: implications to genetic studies of …
LC Faustino, CW Li, M Stefan-Lifshitz, K Kim… - Thyroid, 2020 - liebertpub.com
Background: Thyroglobulin (TG) is a key autoantigen in autoimmune thyroid diseases
(AITD). Several single nucleotide polymorphisms (SNPs) in the TG locus were shown to be …
(AITD). Several single nucleotide polymorphisms (SNPs) in the TG locus were shown to be …