RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Nanoparticles as drug delivery system have received much attention in recent years,
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …

The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …

MicroRNAs play important roles in regulating the gene expression and life cycle of cancer
cells. In particular, miR-21, an oncogenic miRNA is a major player involved in tumor …

Exosomes have shown increasing potential as delivery vesicles for therapy, but challenges
like cost/yield, drug payload, and targeting specificity still exist. Plant derived exosome-like …

Paclitaxel is widely used in cancer treatments, but poor water-solubility and toxicity raise
serious concerns. Here we report an RNA four-way junction nanoparticle with ultra …

Nucleic acids play a central role in all domains of life, either as genetic blueprints or as
regulators of various biochemical pathways. The 826chemical makeup of ribonucleic acid …

Conspectus Nanotechnology's central goal involves the direct control of matter at the
molecular nanometer scale to build nanofactories, nanomachines, and other devices for …

Human genome sequencing revealed that only~ 1.5% of the DNA sequence coded for
proteins. More and more evidence has uncovered that a substantial part of the 98.5% so …