Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase
The phospholipase A2 (PLA2) and l-amino acid oxidase (LAAO) are two major enzymes
found in the venoms from most snake species. These enzymes have been structurally and …
found in the venoms from most snake species. These enzymes have been structurally and …
Past decade study of snake venom L-amino acid oxidase
C Guo, S Liu, Y Yao, Q Zhang, MZ Sun - Toxicon, 2012 - Elsevier
As one of the major protein (enzyme) components of snake venom (SV), l-amino acid
oxidase (LAAO) plays an important role in the toxicities and biological activities for SV …
oxidase (LAAO) plays an important role in the toxicities and biological activities for SV …
[HTML][HTML] Snake venom L-amino acid oxidases: an overview on their antitumor effects
TR Costa, SM Burin, DL Menaldo… - Journal of Venomous …, 2014 - SciELO Brasil
The L-amino acid oxidases (LAAOs) constitute a major component of snake venoms and
have been widely studied due to their widespread presence and various effects, such as …
have been widely studied due to their widespread presence and various effects, such as …
Snake venom toxins: Potential anticancer therapeutics
BC Offor, LA Piater - Journal of Applied Toxicology, 2024 - Wiley Online Library
Snake venom contains a cocktail of compounds dominated by proteins and peptides, which
make up the toxin. The toxin components of snake venom attack several targets in the …
make up the toxin. The toxin components of snake venom attack several targets in the …
[HTML][HTML] Isolation and biochemical, functional and structural characterization of a novel L-amino acid oxidase from Lachesis muta snake venom
The aim of this study was the isolation of the LAAO from Lachesis muta venom (LmLAAO)
and its biochemical, functional and structural characterization. Two different purification …
and its biochemical, functional and structural characterization. Two different purification …
[HTML][HTML] Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in …
CP Silva, TR Costa, RMA Paiva, ACO Cintra… - Journal of Venomous …, 2015 - SciELO Brasil
Abstract Background Phospholipases A 2 (PLA 2 s) are abundant components of snake
venoms that have been extensively studied due to their pharmacological and …
venoms that have been extensively studied due to their pharmacological and …
BjussuLAAO-II, an L-amino acid oxidase from Bothrops jararacussu snake venom, impairs Toxoplasma gondii infection in human trophoblast cells and villous explants …
TA de Melo Fernandes, SC Teixeira, TR Costa… - Microbes and …, 2023 - Elsevier
One-third of the world's population is estimated to be affected by toxoplasmosis. Pregnancy-
related Toxoplasma gondii infection can cause vertical transmission, infect the fetus, and …
related Toxoplasma gondii infection can cause vertical transmission, infect the fetus, and …
[HTML][HTML] CR-LAAO, an L-amino acid oxidase from Calloselasma rhodostoma venom, as a potential tool for developing novel immunotherapeutic strategies against …
TR Costa, DL Menaldo, KF Zoccal, SM Burin… - Scientific Reports, 2017 - nature.com
L-amino acid oxidases from snake venoms have been described to possess various
biological functions. In this study, we investigated the inflammatory responses induced in …
biological functions. In this study, we investigated the inflammatory responses induced in …
[HTML][HTML] King cobra (Ophiophagus hannah) venom L-amino acid oxidase induces apoptosis in PC-3 cells and suppresses PC-3 solid tumor growth in a tumor …
King cobra (Ophiophagus hannah) venom L-amino acid oxidase (OH-LAAO), a heat stable
enzyme, has been shown to exhibit very potent anti-proliferative activity against human …
enzyme, has been shown to exhibit very potent anti-proliferative activity against human …
Exploration of antimicrobial and anticancer activities of L-amino acid oxidase from Egyptian Naja haje venom
WH Salama, AA Abd-Rabou, RI Bassuiny, AE El Hakim… - Toxicon, 2024 - Elsevier
Hepatocellular carcinoma and bacterial resistance are major health burdens nowadays.
Thus, providing new therapies that overcome that resistance is of great interest, particularly …
Thus, providing new therapies that overcome that resistance is of great interest, particularly …