Asthma is different in women

JG Zein, SC Erzurum - Current allergy and asthma reports, 2015 - Springer
Gender differences in asthma incidence, prevalence and severity have been reported
worldwide. After puberty, asthma becomes more prevalent and severe in women, and is …

The allergic asthma phenotype

M Schatz, L Rosenwasser - The Journal of Allergy and Clinical Immunology …, 2014 - Elsevier
Allergic asthma is the most common asthma phenotype. It usually is defined by the presence
of sensitization to environmental allergens, although a clinical correlation between exposure …

Diagnosis and management of NSAID‐Exacerbated Respiratory Disease (N‐ERD)—a EAACI position paper

ML Kowalski, I Agache, S Bavbek, A Bakirtas… - Allergy, 2019 - Wiley Online Library
NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic eosinophilic, inflammatory
disorder of the respiratory tract occurring in patients with asthma and/or chronic …

Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma

EH Bel, SE Wenzel, PJ Thompson… - New England journal …, 2014 - Mass Medical Soc
Background Many patients with severe asthma require regular treatment with oral
glucocorticoids despite the use of high-dose inhaled therapy. However, the regular use of …

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

KF Chung, SE Wenzel, JL Brozek… - European respiratory …, 2014 - Eur Respiratory Soc
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

[HTML][HTML] Baseline features of the Severe Asthma Research Program (SARP III) cohort: differences with age

WG Teague, BR Phillips, JV Fahy, SE Wenzel… - The Journal of Allergy …, 2018 - Elsevier
Background The effect of age on asthma severity is poorly understood. Objectives The
objective of this study was to compare the baseline features of severe and nonsevere …

Involvement and possible role of eosinophils in asthma exacerbation

K Nakagome, M Nagata - Frontiers in immunology, 2018 - frontiersin.org
Eosinophils are involved in the development of asthma exacerbation. Recent studies have
suggested that sputum and blood eosinophil counts are important factors for predicting …

Treatable traits can be identified in a severe asthma registry and predict future exacerbations

VM McDonald, SA Hiles, K Godbout, ES Harvey… - …, 2019 - Wiley Online Library
Background and objective A new taxonomic and management approach, termed treatable
traits, has been proposed for airway diseases including severe asthma. This study examined …

Benefits of omalizumab as add‐on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step …

M Humbert, R Beasley, J Ayres, R Slavin, J Hébert… - Allergy, 2005 - Wiley Online Library
Background: Patients with severe persistent asthma who are inadequately controlled
despite Global Initiative for Asthma (GINA) 2002 step 4 therapy are a challenging population …

Characterization of the severe asthma phenotype by the national heart, lung, and blood institute's severe asthma research program

WC Moore, ER Bleecker, D Curran-Everett… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Severe asthma causes the majority of asthma morbidity. Understanding
mechanisms that contribute to the development of severe disease is important. OBJECTIVE …