Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Inflammation and emotion regulation: a narrative review of evidence and mechanisms in emotion dysregulation disorders

F Petruso, AE Giff, BA Milano, MM De Rossi… - Neuronal …, 2023 - portlandpress.com
Emotion dysregulation (ED) describes a difficulty with the modulation of which emotions are
felt, as well as when and how these emotions are experienced or expressed. It is a focal …

Chronic social defeat alters brain vascular-associated cell gene expression patterns leading to vascular dysfunction and immune system activation

JD Samuels, ML Lotstein, ML Lehmann… - Journal of …, 2023 - Springer
Brain vascular integrity is critical for brain health, and its disruption is implicated in many
brain pathologies, including psychiatric disorders. Brain-vascular barriers are a complex …

[HTML][HTML] Evaluation of serum zonulin and occludin levels in bipolar disorder

S Zengil, E Laloğlu - Psychiatry investigation, 2023 - ncbi.nlm.nih.gov
Objective The etiology of bipolar disorder (BD) is still not fully understood. Little is currently
known about the relationship between the interaction the gastrointestinal system and brain …

[HTML][HTML] Adjunct therapy with probiotics for depressive episodes of bipolar disorder type Ⅰ: A randomized placebo-controlled trial

J Zhang, F Zhu, E Feng, F Wu, X Fang, H Tu… - Journal of Functional …, 2023 - Elsevier
Background Probiotics adjuvant therapy might enhance the efficacy of the conventional
medications of bipolar disorder type Ⅰ (BD-Ⅰ). Methods A randomized double-blind …

Blood-brain barrier disruption: a culprit of cognitive decline?

J Che, Y Sun, Y Deng, J Zhang - Fluids and Barriers of the CNS, 2024 - Springer
Cognitive decline covers a broad spectrum of disorders, not only resulting from brain
diseases but also from systemic diseases, which seriously influence the quality of life and …

[HTML][HTML] Why N, N-Dimethyltryptamine (DMT) Matters: Unique Features and Therapeutic Potential Beyond Classical Psychedelics

C Chaves, RG Dos Santos, SM Dursun… - Frontiers in …, 2024 - frontiersin.org
" Iracema comes with the pot full of the green liquor. The shaman decrees the dreams to
each warrior and distributes the wine of jurema, which carries the brave Tabajara to …

A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome

SE Hurst, E Liktor-Busa, A Moutal, S Parker… - Neuronal …, 2018 - portlandpress.com
We investigated the genome of a 5-year-old male who presented with global developmental
delay (motor, cognitive, and speech), hypotonia, possibly ataxia, and cerebellar hypoplasia …

Reviews in psychiatry 2023: schizophrenia

M Tusconi, D Kätzel, T Sanchez-Gutierrez - Frontiers in Psychiatry, 2024 - frontiersin.org
Several reviews explore the effectiveness of non-pharmacological treatment options in
Schizophrenia. For example, in parallel with standard psychosocial and pharmacological …

Application of an in vitro neuroinflammation model to evaluate the efficacy of magnesium-lithium alloys

K Bhat, H Helmholz, R Willumeit-Römer - Frontiers in Cellular …, 2024 - frontiersin.org
Mg-Li alloys can be promising candidates as bioresorbable Li-releasing implants for bipolar
disorder and other neurodegenerative disorders. In order to compare the therapeutic …