Heck reaction of electronically diverse tertiary alkyl halides

D Kurandina, M Rivas, M Radzhabov… - Organic letters, 2018 - ACS Publications
The efficient Pd-catalyzed Heck reaction of diverse tertiary alkyl halides with alkenes has
been developed. Unactivated tertiary alkyl halides efficiently react at room temperature …

[PDF][PDF] Alcohols in direct carbon-carbon and carbon-heteroatom bond-forming reactions: Recent advances

N Ajvazi, S Stavber - Arkivoc, 2018 - arkat-usa.org
In recent years, nucleophilic substitution of alcohols leading to the formation of the CC and C-
heteroatom bonds has become an attractive process used in the synthesis of organic …

Preparation of 5-methylfurfural from starch in one step by iodide mediated metal-free hydrogenolysis

Y Peng, X Li, T Gao, T Li, W Yang - Green Chemistry, 2019 - pubs.rsc.org
Starch is available in large quantities and at cheap price, especially that from stale rice, root
and tuber crops, etc., which makes it desirable for conversion to value-added products. A …

Rapid in situ generation of 2-(halomethyl)-5-phenylfuran and nucleophilic addition in a microflow reactor

Y Matsuura, S Fuse - Organic & Biomolecular Chemistry, 2024 - pubs.rsc.org
2, 5-Disubstituted furans are frequently found in pharmaceuticals and bioactive natural
products. Nucleophilic substitution reactions on the carbon atom adjacent to the furan ring …

Direct Synthesis of 5‐Methylfurfural from d‐Fructose by Iodide‐Mediated Transfer Hydrogenation

J Xu, X Miao, L Liu, Y Wang, W Yang - ChemSusChem, 2021 - Wiley Online Library
Herein, a robust catalytic system was developed for the green synthesis of 5‐methylfurfural
(5‐MF) by iodide‐mediated transfer hydrogenation. Around 50% of 5‐MF was yielded from d …

Optimization of Substrate‐Analogue Furin Inhibitors

T Ivanova, K Hardes, S Kallis, SO Dahms… - …, 2017 - Wiley Online Library
The proprotein convertase furin is a potential target for drug design, especially for the
inhibition of furin‐dependent virus replication. All effective synthetic furin inhibitors identified …

[PDF][PDF] Halogenation–A Versatile Tool For Drug Synthesis-The Importance Of Developing Effective And Eco-Friendly Reaction Protocols

A Jităreanu, IC Caba, L Agoroaei - Curr. Ana. Biotechnol, 2019 - researchgate.net
The preoccupation for discovering new therapeutic agents is constant and, in this context,
the study of bromine-containing molecules is a research field of great interest. These …

Asymmetric Total Synthesis of (−)‐Stemonamine and Its Stereochemical Stability

S Fujita, K Nishikawa, T Iwata… - … A European Journal, 2018 - Wiley Online Library
The first asymmetric total synthesis of (−)‐stemonamine is described. The key reactions
included intramolecular acylation to construct the seven‐membered ring and a tandem [2+ …

Catalytic halogen bond activation in the benzylic C–H bond iodination with iodohydantoins

SH Combe, A Hosseini, L Song, H Hausmann… - Organic …, 2017 - ACS Publications
This letter presents the side-chain iodination of electron-deficient benzylic hydrocarbons at rt
using N-hydroxyphthalimide (NHPI) as radical initiator and 1, 3-diiodo-5, 5 …

Dual copper-and photoredox-catalysed C (sp2)–C (sp3) coupling

EB McLean, V Gauchot, S Brunen, DJ Burns… - Chemical …, 2019 - pubs.rsc.org
The use of copper catalysis with visible light photoredox catalysis in a cooperative fashion
has recently emerged as a versatile means of developing new C–C bond forming reactions …