Interplay between mechanics and signalling in regulating cell fate

H De Belly, EK Paluch, KJ Chalut - Nature Reviews Molecular Cell …, 2022 - nature.com
Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

The actin cortex at a glance

P Chugh, EK Paluch - Journal of cell science, 2018 - journals.biologists.com
Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …

The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior

V Venturini, F Pezzano, F Catala Castro, HM Häkkinen… - Science, 2020 - science.org
INTRODUCTION Human beings are equipped with multiple senses (sight, hearing, smell,
taste, touch, and proprioception) to help them to react properly to their environment. The …

Tensile forces and mechanotransduction at cell–cell junctions

G Charras - Current Biology, 2018 - cell.com
Cell–cell junctions are specializations of the plasma membrane responsible for physically
integrating cells into tissues. We are now beginning to appreciate the diverse impacts that …

Mechanics of the cellular microenvironment as probed by cells in vivo during zebrafish presomitic mesoderm differentiation

A Mongera, M Pochitaloff, HJ Gustafson… - nature materials, 2023 - nature.com
Tissue morphogenesis, homoeostasis and repair require cells to constantly monitor their
three-dimensional microenvironment and adapt their behaviours in response to local …

Modeling semiflexible polymer networks

CP Broedersz, FC MacKintosh - Reviews of Modern Physics, 2014 - APS
This is an overview of theoretical approaches to semiflexible polymers and their networks.
Such semiflexible polymers have large bending rigidities that can compete with the entropic …

Nanoparticle elasticity regulates phagocytosis and cancer cell uptake

Y Hui, X Yi, D Wibowo, G Yang, APJ Middelberg… - Science …, 2020 - science.org
The ability of cells to sense external mechanical cues is essential for their adaptation to the
surrounding microenvironment. However, how nanoparticle mechanical properties affect cell …

Mechanical regulation of early vertebrate embryogenesis

M Valet, ED Siggia, AH Brivanlou - Nature Reviews Molecular Cell …, 2022 - nature.com
Embryonic cells grow in environments that provide a plethora of physical cues, including
mechanical forces that shape the development of the entire embryo. Despite their …

Biophysical principles of ion-channel-mediated mechanosensory transduction

CD Cox, N Bavi, B Martinac - Cell reports, 2019 - cell.com
Recent rapid progress in the field of mechanobiology has been driven by novel emerging
tools and methodologies and growing interest from different scientific disciplines. Specific …

Materials evolution of bone plates for internal fixation of bone fractures: A review

J Li, L Qin, K Yang, Z Ma, Y Wang, L Cheng… - Journal of Materials …, 2020 - Elsevier
Bone plates play a vital role in bone fracture healing by providing the necessary mechanical
fixation for fracture fragments through modulating biomechanical microenvironment adjacent …