Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Background Studies on tumor-secreted microRNAs point to a functional role of these in
cellular communication and reprogramming of the tumor microenvironment. Uptake of tumor …

Abstract β-Arrestins (βArrs) are intracellular signal regulating proteins. Their expression
level varies in some cancers and they have a significant impact on cancer cell function. In …

Breast cancer is one of the leading causes of morbidity and mortality that is in need of novel
diagnostics and therapeutics. Meta-analysis of microarray data offers promise to combine …

Background Propranolol is the first-choice treatment for severe infantile hemangioma (IH).
However, 10–30% of lesions relapse after propranolol treatment. The mechanisms …

Abstract MicroRNAs (miRNAs), as non-coding molecules, were proved to be correlated with
gene expression in naspharyngeal carcinoma (NPC) development. In this research, a …

Neonatal PMN are qualitatively impaired in functions, yet they frequently reveal augmented
inflammatory reactions during sepsis. Here, we hypothesized that PMN from newborns …

MicroRNAs are biomarkers and potential therapeutic targets for breast cancer. Anacardic
acid (AnAc) is a dietary phenolic lipid that inhibits both MCF-7 estrogen receptor α (ERα) …

Background Hemangioma is a common benign tumor in the childhood; however our
knowledge about the molecular mechanisms of hemangioma development and progression …

Generally, cancer stem cells have epithelial-to-mesenchymal-transition characteristics and
other aggressive properties that cause metastasis. However, there have been no confident …