Lassa fever vaccine candidates: A scoping review of vaccine clinical trials

G Sulis, A Peebles, NE Basta - Tropical Medicine & …, 2023 - Wiley Online Library
Objective Lassa fever (LF) is caused by a viral pathogen with pandemic potential. LF
vaccines have the potential to prevent significant disease in individuals at risk of infection …

The deuce-ace of Lassa Fever, Ebola virus disease and COVID-19 simultaneous infections and epidemics in West Africa: clinical and public health implications

ND Nnaji, H Onyeaka, RC Reuben… - Tropical Medicine and …, 2021 - Springer
Globally, the prevailing COVID-19 pandemic has caused unprecedented clinical and public
health concerns with increasing morbidity and mortality. Unfortunately, the burden of COVID …

A human monoclonal antibody combination rescues nonhuman primates from advanced disease caused by the major lineages of Lassa virus

RW Cross, ML Heinrich, KA Fenton… - Proceedings of the …, 2023 - National Acad Sciences
There are no approved treatments for Lassa fever (LF), which is responsible for thousands of
deaths each year in West Africa. A major challenge in developing effective medical …

Emerging and reemerging infectious diseases: global overview

A Zumla, DSC Hui - Infectious Disease Clinics, 2019 - id.theclinics.com
Background New emerging and reemerging infectious disease outbreaks have continued to
cause much human suffering and loss of life worldwide. During the past 2 decades, several …

Development of a new drug candidate for the inhibition of Lassa virus glycoprotein and nucleoprotein by modification of evodiamine as promising therapeutic agents

S Akash, J Baeza, S Mahmood, N Mukerjee… - Frontiers in …, 2023 - frontiersin.org
The Lassa virus (LASV), an RNA virus prevalent in West and Central Africa, causes severe
hemorrhagic fever with a high fatality rate. However, no FDA-approved treatments or …

[PDF][PDF] Enhancing public awareness of Lassa fever virus through publicity in Cross River State, Nigeria

EE James, IB Inyang, AO Ochelebe - International Journal of Public …, 2022 - abjournals.org
This study centered on enhancing public awareness of Lassa Fever Virus through publicity
in Cross River State. It was aimed at determining the influences of press releases, factsheet …

[HTML][HTML] Lassa fever and COVID‐19 in Africa: a double crisis on the fragile health system

MM Hasan, AC dos Santos Costa… - Journal of medical …, 2021 - ncbi.nlm.nih.gov
Dear Editor, Lassa Fever (LF), an acute zoonotic disease caused by the Lassa fever virus
(LFV), has approximately 2 million annual occurrences with 5000 to 10000 deaths. 1 The …

[HTML][HTML] Exotic viral hepatitis: A review on epidemiology, pathogenesis, and treatment

LPM van Leeuwen, W de Jong, L Doornekamp… - Journal of …, 2022 - Elsevier
Certain “exotic” viruses are known to cause clinical diseases with potential liver involvement.
These include viruses, beyond regular hepatotropic viruses (hepatitis A,-B (D),-C,-E …

Virus persistence after recovery from acute Lassa fever in Nigeria: a 2-year interim analysis of a prospective longitudinal cohort study

A Thielebein, Y Ighodalo, A Taju, T Olokor… - The Lancet …, 2022 - thelancet.com
Background There is anecdotal evidence for Lassa virus persistence in body fluids. We
aimed to investigate various body fluids after recovery from acute Lassa fever, describe the …

Targeting viral genome synthesis as broad-spectrum approach against RNA virus infections

J Huchting - Antiviral Chemistry and Chemotherapy, 2020 - journals.sagepub.com
Zoonotic spillover, ie pathogen transmission from animal to human, has repeatedly
introduced RNA viruses into the human population. In some cases, where these viruses …