Staphylococcus aureus and its food poisoning toxins: characterization and outbreak investigation

JA Hennekinne, ML De Buyser… - FEMS microbiology …, 2012 - academic.oup.com
Staphylococcal food poisoning (SFP) is one of the most common food-borne diseases and
results from the ingestion of staphylococcal enterotoxins (SEs) preformed in food by …

Staphylococcal and streptococcal superantigen exotoxins

AR Spaulding, W Salgado-Pabón… - Clinical microbiology …, 2013 - Am Soc Microbiol
This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …

[HTML][HTML] Multisystem inflammatory syndrome in children and long COVID: the SARS-CoV-2 viral superantigen hypothesis

M Noval Rivas, RA Porritt, MH Cheng, I Bahar… - Frontiers in …, 2022 - frontiersin.org
Multisystem inflammatory syndrome in children (MIS-C) is a febrile pediatric inflammatory
disease that may develop weeks after initial SARS-CoV-2 infection or exposure. MIS-C …

[HTML][HTML] HLA class I–associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children

RA Porritt, L Paschold, MN Rivas… - The Journal of …, 2021 - Am Soc Clin Investig
Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory syndrome
associated with SARS-CoV-2 infection, shares clinical features with toxic shock syndrome …

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

MH Cheng, S Zhang, RA Porritt… - Proceedings of the …, 2020 - National Acad Sciences
Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is a
newly recognized condition in children with recent severe acute respiratory syndrome …

Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

ES Van Amersfoort, TJC Van Berkel… - Clinical microbiology …, 2003 - Am Soc Microbiol
Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

Toxic shock syndrome and bacterial superantigens: an update

JK McCormick, JM Yarwood… - Annual Reviews in …, 2001 - annualreviews.org
▪ Abstract Toxic shock syndrome (TSS) is an acute onset illness characterized by fever, rash
formation, and hypotension that can lead to multiple organ failure and lethal shock, as well …

Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: Structural basis for recognition of B-cell …

M Graille, EA Stura, AL Corper… - Proceedings of the …, 2000 - National Acad Sciences
Staphylococcus aureus produces a virulence factor, protein A (SpA), that contains five
homologous Ig-binding domains. The interactions of SpA with the Fab region of membrane …

[HTML][HTML] Glycolipid antigen induces long-term natural killer T cell anergy in mice

VV Parekh, MT Wilson… - The Journal of …, 2005 - Am Soc Clin Investig
Natural killer T (NKT) cells recognize glycolipid antigens presented by the MHC class I–
related glycoprotein CD1d. The in vivo dynamics of the NKT cell population in response to …

Superantigens: microbial agents that corrupt immunity

M Llewelyn, J Cohen - The Lancet infectious diseases, 2002 - thelancet.com
Microbial Superantigens are a family of protein exotoxins that share the ability to trigger
excessive and aberrant activation of T cells. The best characterised are the staphylococcal …