Polymers have assumed the leading role as substrate materials for microfluidic devices in
recent years. They offer a broad range of material parameters as well as material and …

This Review summarizes methods for constructing systems and structures at micron or
submicron scales that have applications in microbiology. These tools make it possible to …

Conventional cell-based assays in life science and medical applications can be difficult to
maintain functionally over long periods. Microfluidics is an emerging technology with …

The dynamics governing gene regulation have an important role in determining the
phenotype of a cell or organism. From processing extracellular signals to generating internal …

Silicon and glass were the main fabrication materials of microfluidic devices, however,
plastics are on the rise in the past few years. Thermoplastic materials have recently been …

This article describes the fabrication of a microfluidic device for the liquid culture of many
individual nematode worms (Caenorhabditis elegans) in separate chambers. Each chamber …

Bacterial biofilms are among the oldest and most prevalent multicellular life forms on Earth
and are increasingly relevant in research areas related to industrial fouling, medicine and …

Biotechnology process development involves strain testing and improvement steps aimed at
increasing yields and productivity. This necessitates the high-throughput screening of many …

Microorganisms lead social lives and use coordinated chemical and physical interactions to
establish complex communities. Mechanistic insights into these interactions have revealed …

Microscale processing techniques offer the potential to speed up the delivery of new drugs
to the market, reducing development costs and increasing patient benefit. These techniques …