With an aging population, there is a proportional increase in the prevalence of intervertebral
disc diseases. Intervertebral disc diseases are the leading cause of lower back pain and …

Main text We aim to summarize the available evidence on the diagnostic accuracy of
imaging (index test) compared to surgery (reference test) for identifying lumbar disc …

The effect of spinal anatomical anomalies on the efficacy of percutaneous endoscopic
lumbar discectomy (PELD) for disc herniation repair is unclear. This retrospective review …

Background and Objectives: Intervertebral disc degeneration (IDD) is a common cause of
symptomatic axial low back pain. Magnetic resonance imaging (MRI) is currently the …

Many factors may trigger intervertebral disc (IVD) structural failure (intervertebral disc
degeneration (IDD) and endplate changes), including inflammation, infection, dysbiosis, and …

Background. Disorders connected with the musculoskeletal and central nervous system
dysfunction are the most significant clinical problem worldwide. Our earlier research has …

Background Lower back pain affects 75%–85% of people at some point in their lives. The
detection of biochemical changes with sodium (23Na) MRI has potential to enable an earlier …

Background It is generally believed that radiological signs of lumbar degenerative disc
disease (DDD) are associated with increased pain and functional impairment as well as …

Lower back pain is one of the most common causes of a reduced quality of life. Magnetic
resonance imaging (MRI) is the best suited imaging technique to detect causes of that pain …

Based on in silico, in situ, and in vivo studies, this study aims to develop a new method for
the quantitative chemical exchange saturation transfer (qCEST) technique considering multi …