[HTML][HTML] Topology regulatory elements: From shaping genome architecture to gene regulation

LF Chen, HK Long - Current opinion in structural biology, 2023 - Elsevier
The importance of 3D genome topology in the control of gene expression is becoming
increasingly apparent, while regulatory mechanisms remain incompletely understood …

Integrative approaches based on genomic techniques in the functional studies on enhancers

Q Wang, J Zhang, Z Liu, Y Duan… - Briefings in …, 2024 - academic.oup.com
With the development of sequencing technology and the dramatic drop in sequencing cost,
the functions of noncoding genes are being characterized in a wide variety of fields (eg …

Enhancers in Plant Development, Adaptation, and Evolution

BM Beernink, JP Vogel, L Lei - Plant and Cell Physiology, 2024 - academic.oup.com
Understanding plant responses to developmental and environmental cues is crucial for
studying morphological divergence and local adaptation. Gene expression changes …

Transfer Learning in Cancer Genetics, Mutation Detection, Gene Expression Analysis, and Syndrome Recognition

H Ashayeri, N Sobhi, P Pławiak, S Pedrammehr… - Cancers, 2024 - mdpi.com
Simple Summary Transfer learning is a technique utilizing a pre-trained model's knowledge
in a new task. This helps reduce the sample size and time needed for training. These …

The Role of CTCF-Mediated Chromatin Looping in Enhancer-Promoter Communication

C Logie - Epigenetics in Biological Communication, 2024 - Springer
In vertebrates, gene transcription is performed by generic eukaryotic molecular machinery
under influence of sequence-specific DNA-binding transcription factors that control gene …