The neurotransmitter glutamate facilitates neuronal signalling at excitatory synapses.
Glutamate is released from the presynaptic membrane into the synaptic cleft. Across the …

A large subgroup of around 25% of schizophrenia patients suffers from obsessive-
compulsive symptoms (OCS) and about 12% fulfill the diagnostic criteria of an obsessive …

Objective: Many population studies have shown that maternal prenatal nutrition deficiency
may increase the risk of neurodevelopmental disorders in their offspring, but its potential …

Background Synapse-associated protein 90/postsynaptic density protein 95-associated
protein 3 (SAPAP3) is an excitatory postsynaptic protein implicated in the pathogenesis of …

Schizophrenia is a severe neuropsychiatric disorder that affects approximately 0.5–1% of
the population. Response to antipsychotic therapy is highly variable, and it is not currently …

Second generation antipsychotics (SGAs) have been implicated in the de novo emergence
and exacerbation of obsessive-compulsive symptoms (OCS) in patients with schizophrenia …

Abstract Obsessive Compulsive Disorder (OCD) and Obsessive Compulsive Symptoms
(OCS) are known to be highly comorbid with bipolar disorder and schizophrenia. Comorbid …

Discs large‑associated protein 5 (DLGAP5) is a microtubule‑associated protein and is
reported to exert oncogenic role in tumorigenesis, including lung cancer and hepatocellular …

Disc large associated protein 4 (DLGAP4) plays an important role in neurological diseases,
but the role and mechanism of DLGAP4 in hepatocellular carcinoma (HCC) remain unclear …

Aberrantly synchronized neuronal discharges in the brain lead to epilepsy, a devastating
neurological disease whose pathogenesis and mechanism are unclear. SAPAP3, a …