Early diagnosis of Alzheimer's disease: the role of biomarkers including advanced EEG signal analysis. Report from the IFCN-sponsored panel of experts

PM Rossini, R Di Iorio, F Vecchio, M Anfossi… - Clinical …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly with a progressive decline in cognitive function significantly affecting quality of life …

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …

P Lewczuk, P Riederer, SE O'bryant… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

New insights into the genetic etiology of Alzheimer's disease and related dementias

C Bellenguez, F Küçükali, IE Jansen, L Kleineidam… - Nature …, 2022 - nature.com
Abstract Characterization of the genetic landscape of Alzheimer's disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

RS Desikan, CC Fan, Y Wang, AJ Schork… - PLoS …, 2017 - journals.plos.org
Background Identifying individuals at risk for developing Alzheimer disease (AD) is of utmost
importance. Although genetic studies have identified AD-associated SNPs in APOE and …

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

I De Rojas, S Moreno-Grau, N Tesi… - Nature …, 2021 - nature.com
Genetic discoveries of Alzheimer's disease are the drivers of our understanding, and
together with polygenetic risk stratification can contribute towards planning of feasible and …

The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study

SJ van der Lee, FJ Wolters, MK Ikram… - The Lancet …, 2018 - thelancet.com
Background Alzheimer's disease is one of the most heritable diseases in elderly people and
the most common type of dementia. In addition to the major genetic determinant of …

The role of sex and sex hormones in neurodegenerative diseases

E Vegeto, A Villa, S Della Torre, V Crippa… - Endocrine …, 2020 - academic.oup.com
Neurodegenerative diseases (NDs) are a wide class of disorders of the central nervous
system (CNS) with unknown etiology. Several factors were hypothesized to be involved in …

Step by step: towards a better understanding of the genetic architecture of Alzheimer's disease

JC Lambert, A Ramirez, B Grenier-Boley… - Molecular …, 2023 - nature.com
Alzheimer's disease (AD) is considered to have a large genetic component. Our knowledge
of this component has progressed over the last 10 years, thanks notably to the advent of …

A multiomics approach to heterogeneity in Alzheimer's disease: focused review and roadmap

AP Badhwar, GP McFall, S Sapkota, SE Black… - Brain, 2020 - academic.oup.com
Aetiological and clinical heterogeneity is increasingly recognized as a common
characteristic of Alzheimer's disease and related dementias. This heterogeneity complicates …

Dementia in Latin America: paving the way toward a regional action plan

MA Parra, S Baez, L Sedeño… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Across Latin American and Caribbean countries (LACs), the fight against dementia
faces pressing challenges, such as heterogeneity, diversity, political instability, and …