Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain
NR Zuniga, NE Earls, AEA Denos… - PLOS Computational …, 2024 - journals.plos.org
Apolipoprotein E (ApoE) polymorphisms modify the risk of Alzheimer's disease with ApoE4
strongly increasing and ApoE2 modestly decreasing risk relative to the control ApoE3. To …
strongly increasing and ApoE2 modestly decreasing risk relative to the control ApoE3. To …
The effects of age, genotype and diet on hippocampal subfield iron dysregulation and Alzheimer's disease biomarkers in an ApoE mouse model
E Black, A Rasch, T Wimmer, A Li… - European Journal of …, 2023 - Wiley Online Library
Current theories regarding accumulation of Alzheimer's disease‐related deposits of
abnormal intra‐and extracellular proteins include reactions to inflammation and …
abnormal intra‐and extracellular proteins include reactions to inflammation and …
[PDF][PDF] 5.1 Chapter Summary
46 ontologies. We found that ApoE4 and ApoE2 both lead to modified regulation of
mitochondrial membrane proteins. In ApoE4 mice this regulation is not cohesive suggesting …
mitochondrial membrane proteins. In ApoE4 mice this regulation is not cohesive suggesting …