Phthalates (PAEs) are of wide concern because they are commonly used in various plastic
products as plasticizers, and can found their way into the environment. However, their …

Synthetic chemicals currently used in a variety of industrial and agricultural applications are
leading to widespread contamination of the environment. Even though the intended uses of …

Background: There has been increasing interest in the concept that exposures to
environmental chemicals may be contributing factors to the epidemics of diabetes and …

Context: Obesity and diabetes are epidemic in the European Union (EU). Exposure to
endocrine-disrupting chemicals (EDCs) is increasingly recognized as a contributor …

Energy balance involves the adjustment of food intake, energy expenditure and body fat
reserves through homeostatic pathways. These pathways include a multitude of biochemical …

Background: Prospective evidence regarding associations for exposures to bisphenol A
(BPA) and phthalates with type 2 diabetes (T2D) is lacking. Objective: We prospectively …

The prevalence of obesity and type 2 diabetes mellitus epidemics presents a great health
problem worldwide. Beside the changes in diet and decreased physical activity, there is …

Worldwide rates of diabetes and other metabolic diseases have exploded over the last
several decades. Globally, more than 170 million individuals currently suffer from diabetes …

Background: Previous studies have shown that women have higher urinary concentrations
of several phthalate metabolites than do men, possibly because of a higher use of personal …

Several therapeutic agents and industrial chemicals induce liver tumors in rodents through
the activation of the peroxisome proliferator-activated receptor alpha (PPARα). The cellular …