MYC oncogene is a transcription factor with a wide array of functions affecting cellular
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …

Ovarian cancer is the seventh most common gynaecologic malignancy seen in women.
Majority of the patients with ovarian cancer are diagnosed at the advanced stage making …

Mitochondria are essential for tumor growth and progression. However, the heavy demand
for mitochondrial activity in cancer leads to increased production of mitochondrial reactive …

The glucose-regulated proteins (GRPs) are stress-inducible chaperones that mostly reside
in the endoplasmic reticulum or the mitochondria. Recent advances show that the GRPs …

In healthy cells, cytochrome c (Cyt c) is located in the mitochondrial intermembrane/
intercristae spaces, where it functions as an electron shuttle in the respiratory chain and …

The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane
mediates metabolic flow, Ca2+, and cell death signaling between the endoplasmic reticulum …

Among the heat shock proteins (HSP), HSP27, HSP70 and HSP90 are the most studied
stress-inducible HSPs, and are induced in response to a wide variety of physiological and …

The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Stress or heat shock proteins (HSPs) are the most conserved proteins present in both
prokaryotes and eukaryotes. Their expression is induced in response to a wide variety of …

The intracellular location of a protein is crucial to its normal functioning in a cell. Cancer cells
utilize the normal processes of nuclear-cytoplasmic transport through the nuclear pore …