We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

It is estimated that infertility affects 8–12% of couples globally, with a male factor being a
primary or contributing cause in approximately 50% of couples. Causes of male subfertility …

Nitric oxide (NO), a reactive nitrogen species, is a molecule of high physiological as well as
pathological importance. Physiological mechanisms mediated by NO mainly include …

Gastric cancer is a deadly disease and remains the third leading cause of cancer-related
death worldwide. The 5-year overall survival rate of patients with early-stage localized …

One important reason for male infertility is oxidative stress and its destructive effects on
sperm structures and functions. The particular composition of the sperm membrane, rich in …

Male infertility is a complex condition with a strong genetic and epigenetic background. This
review discusses the importance of genetic and epigenetic factors in the pathophysiology of …

Male infertility affects half of infertile couples and, currently, a relevant percentage of cases
of male infertility is considered as idiopathic. Although the male contribution to human …

Arsenic is a potent toxicant, and long-term exposure to inorganic arsenic causes lung
damage. M2 macrophages play an important role in the pathogenesis of pulmonary fibrosis …

Oxidative stress (OS) is a significant cause of DNA fragmentation and is associated with
poor embryo development and recurrent miscarriage. The aim of this study was to compare …

Antioxidants are used in the empirical treatment of infertile men. The aim of this study was to
evaluate the effects of antioxidant therapy on conventional semen parameters and …