TFOS DEWS II pain and sensation report

C Belmonte, JJ Nichols, SM Cox, JA Brock, CG Begley… - The ocular …, 2017 - Elsevier
Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

TFOS DEWS II sex, gender, and hormones report

DA Sullivan, EM Rocha, P Aragona, JA Clayton, J Ding… - The ocular …, 2017 - Elsevier
One of the most compelling features of dry eye disease (DED) is that it occurs more
frequently in women than men. In fact, the female sex is a significant risk factor for the …

BCLA CLEAR-Anatomy and physiology of the anterior eye

LE Downie, S Bandlitz, JPG Bergmanson… - Contact Lens and …, 2021 - Elsevier
A key element of contact lens practice involves clinical evaluation of anterior eye health,
including the cornea and limbus, conjunctiva and sclera, eyelids and eyelashes, lacrimal …

Sex hormones and the dry eye

S Truong, N Cole, F Stapleton… - Clinical and …, 2014 - Taylor & Francis
The greater prevalence of dry eye in women compared to men suggests that sex hormones
may have a role in this condition. This review aims to present evidence for how sex …

Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation

O Mauduit, V Delcroix, T Umazume… - Frontiers in …, 2022 - frontiersin.org
The lacrimal gland (LG) is an exocrine gland that produces the watery part of the tear film
that lubricates the ocular surface. Chronic inflammation, such as Sjögren's syndrome (SS), is …

Lacritin and the tear proteome as natural replacement therapy for dry eye

R Karnati, DE Laurie, GW Laurie - Experimental eye research, 2013 - Elsevier
Tear proteins are potential biomarkers, drug targets, and even biotherapeutics. As a
biotherapeutic, a recombinant tear protein might physiologically rescue the ocular surface …

Tear lipocalin and lipocalin-interacting membrane receptor

BJ Glasgow - Frontiers in Physiology, 2021 - frontiersin.org
Tear lipocalin is a primate protein that was recognized as a lipocalin from the homology of
the primary sequence. The protein is most concentrated in tears and produced by lacrimal …

Ocular surface development and gene expression

SK Swamynathan - Journal of ophthalmology, 2013 - Wiley Online Library
The ocular surface—a continuous epithelial surface with regional specializations including
the surface and glandular epithelia of the cornea, conjunctiva, and lacrimal and meibomian …

Tear production after bilateral main lacrimal gland resection in rabbits

D Bhattacharya, Y Ning, F Zhao… - … & visual science, 2015 - iovs.arvojournals.org
Purpose: This study reports tear compensation observed in rabbits with bilateral resection of
main lacrimal gland (LG) and explored the potential mechanisms. Methods: Dry eye …

Biology of the eyelash hair follicle: an enigma in plain sight

R Paus, I Burgoa, CI Platt, T Griffiths… - British Journal of …, 2016 - academic.oup.com
Because of their crucial impact on our perception of beauty, eyelashes constitute a prime
target for the cosmetic industry. However, when compared with other hair shafts and the mini …