The introduction of the E Factor in 1992 focussed attention on the problem of waste
generation, defined as everything but the desired product, in chemicals manufacture and …

Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

The efficiency, selectivity and sustainability benefits offered by enzymes are enticing
chemists to consider biocatalytic transformations to complement or even supplant more …

The pharmaceutical industry, driven by an increasing need to deliver new and more effective
medicines to patients, is increasingly turning to the use of engineered biocatalysts for both …

Chiral amine diastereomers are ubiquitous in pharmaceuticals and agrochemicals, yet their
preparation often relies on low-efficiency multi-step synthesis. These valuable compounds …

Biobased furans, such as furfural, 5-hydroxymethylfurfural, and 2, 5-furandicarboxylic acid,
are recognized as the top-value platform chemicals in the valorization of biomass to …

Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

Alkaloids from plants are characterised by structural diversity and bioactivity, and maintain a
privileged position in both modern and traditional medicines. In recent years, there have …

Finding faster and simpler ways to screen protein sequence space to enable the
identification of new biocatalysts for asymmetric synthesis remains both a challenge and a …