Process analytical technologies and self-optimization algorithms in automated pharmaceutical continuous manufacturing

P Liu, H Jin, Y Chen, D Wang, H Yan, M Wu… - Chinese Chemical …, 2024 - Elsevier
The pharmaceutical industry is now paying increased attention to continuous manufacturing.
While the revolution to continuous and automated manufacturing is deepening in most of the …

Continuous flow synthesis of pyridinium salts accelerated by multi-objective Bayesian optimization with active learning

JH Dunlap, JG Ethier, AA Putnam-Neeb, S Iyer… - Chemical …, 2023 - pubs.rsc.org
We report a human-in-the-loop implementation of the multi-objective experimental design
via a Bayesian optimization platform (EDBO+) towards the optimization of butylpyridinium …

Continuous Flow Synthesis of Substituted 3, 4-Propylenedioxythiophene Derivatives

DL Tarange, N Nayak, A Kumar - Organic Process Research & …, 2023 - ACS Publications
We report a continuous flow method for the process intensification of commercially important
propylenedioxythiophene (ProDOT) monomers. A new four-step synthetic route was …

[HTML][HTML] Additive manufacturing technologies applied to the electrochemical valorization of biomass

G Palmara, D Carvajal, M Zanatta, E Mas-Marza… - Current Research in …, 2023 - Elsevier
Biomass valorization is gaining recognition as a sustainable and easily accessible
renewable option to produce fuels and chemicals non-derived from fossil fuels, thus …