Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery.
However, cancers often develop resistance against drugs, leading to failure of treatment and …

The CRISPR/Cas9 system is an RNA-based adaptive immune system in bacteria and
archaea. Various studies have shown that it is possible to target a wide range of human …

Background The molecular mechanisms driving hepatocellular carcinoma (HCC) remain
largely unclear. As one of the major epitranscriptomic modifications, N 6-methyladenosine …

Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …

Breast cancer (BC) as one of the most common causes of human deaths among women, is
always considered one of the global health challenges. Despite various advances in …

Abstract Background Circular RNAs (circRNAs) represent a novel type of regulatory RNA
characterized by high evolutionary conservation and stability. CircRNAs are expected to be …

Cell type-specific drug delivery is a straightforward strategy to achieve targeted cancer
therapy and reduce side effects. Hyaluronic acid (HA), an US Food and Drug Administration …

Chemotherapy is currently one of the most effective methods in clinical cancer treatment.
However, chemotherapy resistance is an important reason for poor chemotherapy efficacy …

Melatonin is an important naturally occurring hormone in mammals. Melatonin-mediated
biological effects include the regulation of circadian rhythms, which is important for optimal …

Triple-negative breast cancer (TNBC) causes great suffering to patients because of its
heterogeneity, poor prognosis, and chemotherapy resistance. Ferroptosis is characterized …