The interplay of mitophagy and inflammation in Duchenne muscular dystrophy
AL Reid, MS Alexander - Life, 2021 - mdpi.com
Duchenne muscular dystrophy (DMD) is an X-linked neuromuscular disease caused by a
pathogenic disruption of the DYSTROPHIN gene that results in non-functional dystrophin …
pathogenic disruption of the DYSTROPHIN gene that results in non-functional dystrophin …
The new challenge of “exercise+ X ″therapy for Duchenne muscular dystrophy—Individualized identification of exercise tolerance and precise implementation of …
Y Su, Y Song - Frontiers in Physiology, 2022 - frontiersin.org
Duchenne muscular dystrophy (DMD) is an X-linked recessive fatal muscular disease. Gene
therapy, cell therapy, and drug therapy are currently the most widely used treatments for …
therapy, cell therapy, and drug therapy are currently the most widely used treatments for …
Running improves muscle mass by activating autophagic flux and inhibiting ubiquitination degradation in mdx mice
S Zhou, S Lei, Y She, H Shi, Y Li, X Zhou, R Chen - Gene, 2024 - Elsevier
Background Exercise therapy can improve muscle mass, strengthen muscle and
cardiorespiratory function, and may be an excellent adjunctive treatment option for …
cardiorespiratory function, and may be an excellent adjunctive treatment option for …
Antioxidant effects of LEDT in dystrophic muscle cells: involvement of PGC-1α and UCP-3 pathways
GL da Rocha, DSPSF Guimarães, MV da Cruz… - Photochemical & …, 2024 - Springer
Purpose Reactive oxygen species and mitochondrial dysfunction play a crucial role in the
pathophysiology of Duchenne muscular dystrophy (DMD). The light-emitting diode therapy …
pathophysiology of Duchenne muscular dystrophy (DMD). The light-emitting diode therapy …
Effects of Dityrosine on Lactic Acid Metabolism in Mice Gastrocnemius Muscle During Endurance Exercise via the Oxidative Stress-Induced Mitochondria Damage
Q Xia, J Lan, Y Pan, Y Wang, T Song… - Journal of Agricultural …, 2024 - ACS Publications
Dityrosine (Dityr) has been detected in commercial food as a product of protein oxidation
and has been shown to pose a threat to human health. This study aims to investigate …
and has been shown to pose a threat to human health. This study aims to investigate …
Tempol differential effect on prostate cancer inflammation: In vitro and in vivo evaluation
Background Tempol is a redox‐cycling nitroxide that acts directly on inflammation. However,
few studies have reported the use of tempol in prostate cancer (PCa). The present study …
few studies have reported the use of tempol in prostate cancer (PCa). The present study …
Antioxidant effects of bis-indole alkaloid indigo and related signaling pathways in the experimental model of Duchenne muscular dystrophy
DS Mizobuti, GL da Rocha, HNM da Silva… - Cell Stress and …, 2022 - Springer
Indigo is a bis-indolic alkaloid that has antioxidant and anti-inflammatory effects reported in
literature and is a promissory compound for treating chronic inflammatory diseases. This fact …
literature and is a promissory compound for treating chronic inflammatory diseases. This fact …
LEDT and Idebenone treatment modulate autophagy and improve regenerative capacity in the dystrophic muscle through an AMPK-pathway
HNM Silva, EM Fernandes, VA Pereira, DS Mizobuti… - Plos one, 2024 - journals.plos.org
Purpose Considering the difficulties and challenges in Duchenne muscular dystrophy
(DMD) treatment, such as the adverse effects of glucocorticoids, which are the main medical …
(DMD) treatment, such as the adverse effects of glucocorticoids, which are the main medical …
Cilostazol attenuates oxidative stress and apoptosis in the quadriceps muscle of the dystrophic mouse experimental model
TA Hermes, RD Mâncio, DS Mizobutti… - International journal …, 2023 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is the most severe and frequent form of muscular
dystrophy. The mdx mouse is one of the most widely used experimental models to …
dystrophy. The mdx mouse is one of the most widely used experimental models to …
Tempol effect on oxidative and mitochondrial markers in preclinical models for prostate cancer
IMU Rossetto, FR Santos, HM da Silva… - Toxicology …, 2024 - academic.oup.com
Background Tempol is a redox-cycling nitroxide considered a potent antioxidant. The
present study investigated the tempol effects on oxidative stress and mitochondrial markers …
present study investigated the tempol effects on oxidative stress and mitochondrial markers …