The aging-associated decline of biological functions represents an important contributor to
the increase in morbidity and mortality of human beings. Of these biological functions …

Telomere length (TL) is a dynamic marker that reflects genetic predispositions together with
the environmental conditions of an individual. It is closely related to longevity and a number …

Genetic studies on telomere length are important for understanding age-related diseases.
Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here …

Genetic factors underlying leukocyte telomere length (LTL) may provide insights into
telomere homeostasis, with direct links to disease susceptibility. Genetic evaluation of …

Background Adherence to healthy lifestyles/behaviours promotes healthy ageing. However,
little is known about whether age, sex and/or race/ethnicity moderate associations of …

Background Telomere maintenance is increasingly recognized as being fundamental to
glioma oncogenesis with longer leukocyte telomere length (LTL) reported to increase risk of …

Genome-wide association studies (GWAS) have become well-powered to detect loci
associated with telomere length. However, no prior work has validated genes nominated by …

Health and survival are key goals for selective breeding in farm animals. Progress, however,
is often limited by the low heritability of these animal fitness traits in addition to measurement …

The role of low frequency variants associated with telomere length homeostasis in chronic
diseases and mortalities is relatively understudied in the East-Asian population. Here we …

Social and economic disadvantage are hypothesized to increase the risk of disease and
death via accelerated biological aging. Given that US blacks are socially and economically …