Rational design of immunomodulatory hydrogels for chronic wound healing
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
Biomimetic peptide self-assembly for functional materials
Natural biomolecular systems have evolved to form a rich variety of supramolecular
materials and machinery fundamental to cellular function. The assembly of these structures …
materials and machinery fundamental to cellular function. The assembly of these structures …
Immunomodulatory biomaterials for tissue repair
R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
Drug delivery by supramolecular design
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
Designing hydrogels for immunomodulation in cancer therapy and regenerative medicine
Z Zhang, C He, X Chen - Advanced Materials, 2024 - Wiley Online Library
The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …
Amino acids and peptide‐based supramolecular hydrogels for three‐dimensional cell culture
XQ Dou, CL Feng - Advanced Materials, 2017 - Wiley Online Library
Supramolecular hydrogels assembled from amino acids and peptide‐derived hydrogelators
have shown great potential as biomimetic three‐dimensional (3D) extracellular matrices …
have shown great potential as biomimetic three‐dimensional (3D) extracellular matrices …
[HTML][HTML] Self-assemble peptide biomaterials and their biomedical applications
J Chen, X Zou - Bioactive materials, 2019 - Elsevier
Inspired by self-assembling peptides found in native proteins, deliberately designed
engineered peptides have shown outstanding biocompatibility, biodegradability, and …
engineered peptides have shown outstanding biocompatibility, biodegradability, and …
Self-assembling multidomain peptide nanofibers for delivery of bioactive molecules and tissue regeneration
AN Moore, JD Hartgerink - Accounts of chemical research, 2017 - ACS Publications
Conspectus Multidomain peptides (MDPs) are a class of self-assembling peptides that are
organized in a β-sheet motif, resulting in a nanofibrous architecture. This structure is …
organized in a β-sheet motif, resulting in a nanofibrous architecture. This structure is …
Biomaterial-driven in situ cardiovascular tissue engineering—a multi-disciplinary perspective
TB Wissing, V Bonito, CVC Bouten… - NPJ Regenerative …, 2017 - nature.com
There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …
Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications
Macrophages are key players in many physiological scenarios including tissue
homeostasis. In response to injury, typically the balance between macrophage sub …
homeostasis. In response to injury, typically the balance between macrophage sub …