Rational design of immunomodulatory hydrogels for chronic wound healing

M Kharaziha, A Baidya, N Annabi - Advanced Materials, 2021 - Wiley Online Library
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

Biomimetic peptide self-assembly for functional materials

A Levin, TA Hakala, L Schnaider… - Nature Reviews …, 2020 - nature.com
Natural biomolecular systems have evolved to form a rich variety of supramolecular
materials and machinery fundamental to cellular function. The assembly of these structures …

Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Designing hydrogels for immunomodulation in cancer therapy and regenerative medicine

Z Zhang, C He, X Chen - Advanced Materials, 2024 - Wiley Online Library
The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …

Amino acids and peptide‐based supramolecular hydrogels for three‐dimensional cell culture

XQ Dou, CL Feng - Advanced Materials, 2017 - Wiley Online Library
Supramolecular hydrogels assembled from amino acids and peptide‐derived hydrogelators
have shown great potential as biomimetic three‐dimensional (3D) extracellular matrices …

[HTML][HTML] Self-assemble peptide biomaterials and their biomedical applications

J Chen, X Zou - Bioactive materials, 2019 - Elsevier
Inspired by self-assembling peptides found in native proteins, deliberately designed
engineered peptides have shown outstanding biocompatibility, biodegradability, and …

Self-assembling multidomain peptide nanofibers for delivery of bioactive molecules and tissue regeneration

AN Moore, JD Hartgerink - Accounts of chemical research, 2017 - ACS Publications
Conspectus Multidomain peptides (MDPs) are a class of self-assembling peptides that are
organized in a β-sheet motif, resulting in a nanofibrous architecture. This structure is …

Biomaterial-driven in situ cardiovascular tissue engineering—a multi-disciplinary perspective

TB Wissing, V Bonito, CVC Bouten… - NPJ Regenerative …, 2017 - nature.com
There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …

Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications

MM Alvarez, JC Liu, G Trujillo-de Santiago… - Journal of Controlled …, 2016 - Elsevier
Macrophages are key players in many physiological scenarios including tissue
homeostasis. In response to injury, typically the balance between macrophage sub …