[HTML][HTML] Hallmarks of metabolic reprogramming and their role in viral pathogenesis

CNS Allen, SP Arjona, M Santerre, BE Sawaya - Viruses, 2022 - mdpi.com
Metabolic reprogramming is a hallmark of cancer and has proven to be critical in viral
infections. Metabolic reprogramming provides the cell with energy and biomass for large …

[HTML][HTML] Triggers for the Nrf2/ARE signaling pathway and its nutritional regulation: Potential therapeutic applications of ulcerative colitis

H Liu, LJ Johnston, F Wang, X Ma - International journal of molecular …, 2021 - mdpi.com
Ulcerative colitis (UC), which affects millions of people worldwide, is characterized by
extensive colonic injury involving mucosal and submucosal layers of the colon. Nuclear …

Low-dose exposure to phytosynthesized gold nanoparticles combined with glutamine deprivation enhances cell death in the cancer cell line HeLa via oxidative stress …

A Prasad, A Khatua, YK Mohanta, M Saravanan… - Nanoscale, 2022 - pubs.rsc.org
Cancer cells use nutrients like D-glucose (Glc) and L-glutamine (Q) more efficiently for their
development. This increased nutritional dependency of malignant cells has been commonly …

[HTML][HTML] Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice

D Wu, S Su, X Zha, Y Wei, G Yang, Q Huang, Y Yang… - Redox Biology, 2023 - Elsevier
Mucus forms the first line of defence of the intestinal mucosa barrier, and mucin is its core
component. Glutamine is a vital energy substance for goblet cells; it can promote mucus …

[HTML][HTML] Glutamine Metabolism and Prostate Cancer

HHH Erb, N Polishchuk, O Stasyk, U Kahya… - Cancers, 2024 - mdpi.com
Simple Summary Glutamine (Gln) plays a critical role in the development and progression of
prostate cancer (PCa). Non-malignant prostate cells are not addicted to Gln, but PCa cells …

[HTML][HTML] Fundamental role of pentose phosphate pathway within the endoplasmic reticulum in glutamine addiction of triple-negative breast cancer cells

C Marini, V Cossu, S Carta, E Greotti, D Gaglio… - Antioxidants, 2022 - mdpi.com
Cancer utilization of large glutamine equivalents contributes to diverging glucose-6-P flux
toward the pentose phosphate shunt (PPP) to feed the building blocks and the antioxidant …

[HTML][HTML] Glutamine starvation affects cell cycle, oxidative homeostasis and metabolism in colorectal cancer cells

M Spada, C Piras, G Diana, VP Leoni, DV Frau… - Antioxidants, 2023 - mdpi.com
Cancer cells adjust their metabolism to meet energy demands. In particular, glutamine
addiction represents a distinctive feature of several types of tumors, including colorectal …

[HTML][HTML] Ginseng-derived nanoparticles inhibit lung cancer cell epithelial mesenchymal transition by repressing pentose phosphate pathway activity

L Yang, W Jin, X Tang, S Zhang, R Ma, D Zhao… - Frontiers in …, 2022 - frontiersin.org
It is unclear whether ginseng-derived nanoparticles (GDNPs) can prevent tumor cell
epithelial-mesenchymal transition (EMT). Here, we describe typical characteristics of GDNPs …

[HTML][HTML] In-silico molecular interactions among the secondary metabolites of Caulerpa spp. and colorectal cancer targets

N Mert-Ozupek, G Calibasi-Kocal, N Olgun… - Frontiers in …, 2022 - frontiersin.org
Caulerpa spp. secrete more than thirty different bioactive chemicals which have already
been used in cancer treatment research since they play a pivotal role in cancer metabolism …

Tracing the electron flow in redox metabolism: The appropriate distribution of electrons is essential to maintain redox balance in cancer cells

M Ying, X Hu - Seminars in Cancer Biology, 2022 - Elsevier
Cancer cells are characterized by sustained proliferation, which requires a huge demand of
fuels to support energy production and biosynthesis. Energy is produced by the oxidation of …