Mucoadhesive carriers for oral drug delivery

R Kumar, T Islam, M Nurunnabi - Journal of Controlled Release, 2022 - Elsevier
Among the various dosage forms, oral medicine has extensive benefits including ease of
administration and patients' compliance, over injectable, suppositories, ocular and nasal …

Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems

DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …

Advances in mucoadhesion and mucoadhesive polymers

VV Khutoryanskiy - Macromolecular bioscience, 2011 - Wiley Online Library
Mucoadhesion is the ability of materials to adhere to mucosal membranes in the human
body and provide a temporary retention. This property has been widely used to develop …

[HTML][HTML] Formulation strategies to improve the efficacy of intestinal permeation enhancers

S Maher, DJ Brayden - Advanced Drug Delivery Reviews, 2021 - Elsevier
The use of chemical permeation enhancers (PEs) is the most widely tested approach to
improve oral absorption of low permeability active agents, as represented by peptides …

Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature

C Leichner, M Jelkmann… - Advanced Drug Delivery …, 2019 - Elsevier
Thiolated polymers designated “thiomers” are obtained by covalent attachment of thiol
functionalities on the polymeric backbone of polymers. In 1998 these polymers were first …

Oral delivery of therapeutic protein/peptide for diabetes–future perspectives

MR Rekha, CP Sharma - International journal of pharmaceutics, 2013 - Elsevier
Diabetes is a metabolic disease and is a major cause of mortality and morbidity in epidemic
proportions. A type I diabetic patient is dependent on daily injections of insulin, for survival …

Photo-click crosslinked hydrogel containing MgO2-loaded PLGA microsphere with concurrent magnesium and oxygen release for bone tissue engineering

SAS Nasrollah, R Karimi-Soflou, A Karkhaneh - Materials Today Chemistry, 2023 - Elsevier
Overcoming hypoxia and providing a proper microenvironment for osteogenic differentiation
are the most critical challenges in bone tissue engineering (BTE). Hydrogels with the …

Assessment of test methods evaluating mucoadhesive polymers and dosage forms: An overview

C Woertz, M Preis, J Breitkreutz… - European Journal of …, 2013 - Elsevier
Oral mucoadhesive preparations have gained increasing importance in the last decades, by
reason of numerous advantages like easy application, discrete handling and no swallowing …

The electrostimulation and scar inhibition effect of chitosan/oxidized hydroxyethyl cellulose/reduced graphene oxide/asiaticoside liposome based hydrogel on …

F Zheng, R Li, Q He, K Koral, J Tao, L Fan… - Materials Science and …, 2020 - Elsevier
The application of hollow nerve conduits in the repair of peripheral nerve defects is effected
by inferior recovery, and nerve extension is hampered by the scar tissue generated during …

Mucoadhesive maleimide-functionalised liposomes for drug delivery to urinary bladder

DB Kaldybekov, P Tonglairoum, P Opanasopit… - European Journal of …, 2018 - Elsevier
Intravesical drug administration is used to deliver chemotherapeutic agents via a catheter to
treat bladder cancer. The major limitation of this treatment is poor retention of the drug in the …