Four-membered monocyclic aza-heterocycles, 1 despite their indisputable importance as
bioactive compounds and pharmaceutical tools, have received by the chemical community …

The importance and prevalance of O-, N-, and S-atom containing saturated four-membered
ring motifs in biologically active molecules and potential therapeutics continues to drive …

A facile approach for the synthesis of enantiopure γ-amino nitriles by copper-catalyzed
aminocyanation of arylcyclopropanes is disclosed, which undergoes the highly …

A simple one-pot, two-step strategy for the synthesis of tetrahydro-1 H-azepino [4, 3, 2-cd]
indoles via Lewis acid-catalyzed SN2-type ring opening of activated azetidines with 4 …

In this article, a direct access to β-amino nitriles from unactivated imines and alkyl nitriles by
electrochemical radical–radical cross-coupling was described for the first time. The use of …

A highly regio-and stereoselective strategy for the syntheses in high yield and
enantioselectivity of a variety of substituted nonracemic morpholines and their homologues …

Cycloadditions of alkynyl ketones with N-tosylimines catalyzed by Lewis bases to synthesize
azetidines and pyrrolidines were systematically described. In the reaction of alkynyl ketones …

Highly efficient Ni-catalyzed asymmetric hydrogenation of cyclic N-sulfonyl ketimino esters
was, for the first time, successfully developed, providing various chiral α-monosubstituted α …

Lewis acid-mediated highly regioselective SN2-type ring-opening of 2-aryl-N-tosylazetidines
with alcohols to afford various 1, 3-amino ethers in excellent yields with good enantiomeric …

A highly efficient strategy for Cu (OTf) 2-mediated ring-opening of 2-aryl-N-tosylazetidines in
polar and coordinating solvents followed by an unprecedented rearrangement to substituted …