Interstitial cells: regulators of smooth muscle function

KM Sanders, SM Ward, SD Koh - Physiological reviews, 2014 - journals.physiology.org
Smooth muscles are complex tissues containing a variety of cells in addition to muscle cells.
Interstitial cells of mesenchymal origin interact with and form electrical connectivity with …

Calcium signalling in Cajal-like interstitial cells of the lower urinary tract

BT Drumm, SD Koh, KE Andersson, SM Ward - Nature reviews Urology, 2014 - nature.com
Interstitial cells of Cajal (ICC) serve several critical physiological roles in visceral smooth
muscle organs, including acting as electrical pacemakers to modulate phasic contractile …

[HTML][HTML] Long range physical cell-to-cell signalling via mitochondria inside membrane nanotubes: a hypothesis

F Scholkmann - Theoretical Biology and Medical Modelling, 2016 - Springer
Coordinated interaction of single cells by cell-to-cell communication (signalling) enables
complex behaviour necessary for the functioning of multicellular organisms. A quite newly …

[HTML][HTML] Calcium signaling in interstitial cells: focus on telocytes

BM Radu, A Banciu, DD Banciu, M Radu… - International journal of …, 2017 - mdpi.com
In this review, we describe the current knowledge on calcium signaling pathways in
interstitial cells with a special focus on interstitial cells of Cajal (ICCs), interstitial Cajal-like …

Interstitial cells of Cajal mediate excitatory sympathetic neurotransmission in guinea pig prostate

J Wang, G Ding, Q Wang - Cell and tissue research, 2013 - Springer
Morphological and functional studies have confirmed that interstitial cells of Cajal (ICCs) are
involved in many enteric motor neurotransmission pathways. Recent investigations have …

Commonality and heterogeneity of pacemaker mechanisms in the male reproductive organs

H Hashitani, M Takeya… - The Journal of …, 2024 - Wiley Online Library
During emission, the first phase of ejaculation, smooth muscle in organs of the male
reproductive tract (MRT) vigorously contract upon sympathetic nerve excitation to expel …

Propagation of Pacemaker Activity and Peristaltic Contractions in the Mouse Renal Pelvis Rely on Ca2+-activated Cl Channels and T-Type Ca2+ Channels

N Grainger, CC Shonnard, SK Quiggle, EB Fox… - Function, 2022 - academic.oup.com
The process of urine removal from the kidney occurs via the renal pelvis (RP). The RP
demarcates the beginning of the upper urinary tract and is endowed with smooth muscle …

T-type Ca2+ channels and the urinary and male genital tracts

CH Fry, RI Jabr - Pflügers Archiv-European Journal of Physiology, 2014 - Springer
T-type Ca 2+ channels are widely expressed throughout the urinary and male genital tracts,
generally alongside L-type Ca 2+ channels. The use of pharmacological blockers of these …

Voltage‐operated Ca2+ currents and Ca2+‐activated Cl currents in single interstitial cells of the guinea‐pig prostate

RJ Lang, MA Tonta, H Takano, H Hashitani - BJU international, 2014 - Wiley Online Library
Objective To investigate the expression of 'T‐type'and 'L‐type'voltage‐operated Ca2+
channels in single interstitial cells of the guinea‐pig prostate. Material and Methods Whole …

[HTML][HTML] Спонтанная ритмическая активность органов мочевой системы: роль интерстициальных клеток, биологическая значимость, патофизиологические …

ВИ Кирпатовский, ЕВ Фролова… - … и клиническая урология, 2012 - cyberleninka.ru
Существование спонтанной ритмической активности мочевых путей известно давно.
Первоначально была обнаружена периодическая электрическая активность почечной …