1, 2, 3‐Triazole hybrids as anticancer agents: A review

MM Alam - Archiv der Pharmazie, 2022 - Wiley Online Library
Despite the advancements in the development of anticancer agents, more effective and
safer anticancer drugs still need to be developed as the current agents cause unwanted side …

1, 2, 3-triazole derivatives with anti-breast cancer potential

X Wu, J Wang, S Xia, S Cheng… - Current Topics in …, 2022 - ingentaconnect.com
Breast cancer is one of the most prevalent malignant diseases, and one of the main causes
of mortality among women across the world. Despite advances in chemotherapy, drug …

Spectroscopic characterization, cyclic voltammetry, biological investigations, MOE, and gaussian calculations of VO (II), Cu (II), and Cd (II) heteroleptic complexes

AG Al-Harazie, EA Gomaa, RR Zaky… - ACS …, 2023 - ACS Publications
A novel hydrazone ligand (o-H2BMP) N-(benzo [d] thiazol-2-yl)-3-oxo-3-(2-(1-(pyridin-2-yl)
ethylidene) hydrazinyl) propanamide alongside its Cu (II), Cd (II), and VO (II) complexes …

Benzenesulfonamide-thiazole system bearing an azide group: Synthesis and evaluation of its optical nonlinear responses

HH Al-Hujaj, QMA Hassan, FA Almashal, HA Sultan… - Optik, 2022 - Elsevier
Objective The current study aims to find a material that has high nonlinear optical properties
to be used in photonic applications. Methods The synthesis and characterization of …

Design, cytotoxic effects on breast cancer cell line (MDA-MB 231), and molecular docking of some maleimide-benzenesulfonamide derivatives

AM Dhumad, AM Jassem, RA Alharis… - Journal of the Indian …, 2021 - Elsevier
A group of novel maleimide-benzenesulfonamide derivatives 3a-d was designed and
synthesized for their evaluation as a potential anti-breast cancer agent. The structures of …

Isatin-indole hybrid molecule: A simple synthesis to design an efficient NLO material

GS Yaqoob, QMA Hassan, AM Jassem, HA Sultan… - Optical Materials, 2024 - Elsevier
The isatin-indole hybrid molecule, referred to as molecule 5,(Z)-3-((4-((4-((E)-((1H-indol-3-yl)
methylene) amino) phenyl) sulfonyl) phenyl) imino) indolin-2-one (C 29 H 20 N 4 O 3 S), is …

Synthesis, antiproliferative, antioxidant activities, in silico studies, DFT analysis and molecular dynamics simulation of novel 1-(4-chlorobenzhydryl) piperazine …

NA Al-Masoudi, RS Jihad, NA Abdul-Rida… - Journal of Molecular …, 2024 - Elsevier
Abstract A series of 1-(4-chlorobenzhydryl) piperazine derivatives 3–10 were synthesized
and characterized both spectroscopically and structurally to investigate their antiproliferative …

An alternative technique for cyclization synthesis, in vitro anti-esophageal cancer evaluation, and molecular docking of novel thiazolidin-4-one derivatives

AM Jassem, AM Dhumad, JK Salim, HA Jabir - Journal of Molecular …, 2023 - Elsevier
In this work, two novel series of thiazolidin-4-one derivatives (9a–e and 10a–e) constituting
ten compounds were synthesized under batch and ultrasound irradiation. It is found that the …

Recent advances in synthesis and anticancer potential of triazole-containing scaffolds

DS Bhagat, GS Bumbrah, PA Chawla… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Cancer is the most lethal disease that may be found anywhere globally. Approximately 10%
of individuals die due to cancer of various types, with 19.3 million new cancer cases and 10 …

Recent advances in triazole-benzenesulfonamide hybrids and their biological activities

Chander, Monika, PK Sharma, S Ram - Medicinal Chemistry Research, 2023 - Springer
Hybridization is the process of fusion of two or more existing moieties to make a single
molecule. Triazoles and benzenesulfonamides are the useful pharmacological agents …