Circadian rhythms of the hypothalamus: from function to physiology

R Van Drunen, K Eckel-Mahan - Clocks & sleep, 2021 - mdpi.com
The nearly ubiquitous expression of endogenous 24 h oscillations known as circadian
rhythms regulate the timing of physiological functions in the body. These intrinsic rhythms …

Regulation and function of extra‐SCN circadian oscillators in the brain

K Begemann, AM Neumann, H Oster - Acta physiologica, 2020 - Wiley Online Library
Most organisms evolved endogenous, so called circadian clocks as internal timekeeping
mechanisms allowing them to adapt to recurring changes in environmental demands …

Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant

M Izumo, M Pejchal, AC Schook, RP Lange… - Elife, 2014 - elifesciences.org
In order to assess the contribution of a central clock in the hypothalamic suprachiasmatic
nucleus (SCN) to circadian behavior and the organization of peripheral clocks, we …

The mysterious food-entrainable oscillator: insights from mutant and engineered mouse models

JS Pendergast, S Yamazaki - Journal of biological rhythms, 2018 - journals.sagepub.com
The food-entrainable oscillator (FEO) is a mysterious circadian clock because its anatomical
location (s) and molecular timekeeping mechanism are unknown. Food anticipatory activity …

[HTML][HTML] The role of circadian clocks in metabolic disease

MD Li, CM Li, Z Wang - The Yale journal of biology and medicine, 2012 - ncbi.nlm.nih.gov
The circadian clock is a highly conserved timing system, resonating physiological processes
to 24-hour environmental cycles. Circadian misalignment is emerging as a risk factor of …

Circadian clocks, diets and aging

A Chaudhari, R Gupta, K Makwana… - Nutrition and healthy …, 2017 - content.iospress.com
Diets and feeding regimens affect many physiological systems in the organism and may
contribute to the development or prevention of various pathologies including cardiovascular …

Competing clocks: metabolic status moderates signals from the master circadian pacemaker

ID Blum, EW Lamont, A Abizaid - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Food anticipation and its behavioural manifestation, food anticipatory activity (FAA), require
entrainment of a suprachiasmatic nucleus (SCN) independent circadian mechanism, a food …

An endocrinologist's guide to the clock

MJ Prasai, I Pernicova, PJ Grant… - The Journal of Clinical …, 2011 - academic.oup.com
Context: It has long been recognized that a “biological clock” residing in the suprachiasmatic
nucleus controls circadian or daily variations in physiological processes. Old observations …

Behavioral and neural correlates of acute and scheduled hunger in C57BL/6 mice

CM Gallardo, CT Hsu, KM Gunapala, M Parfyonov… - PloS one, 2014 - journals.plos.org
In rodents, daily feeding schedules induce food anticipatory activity (FAA) rhythms with
formal properties suggesting mediation by food-entrained circadian oscillators (FEOs). The …

Time-restricted feeding entrains long-term behavioral changes through the IGF2-KCC2 pathway

Q Zhai, Y Zeng, Y Gu, Z Li, T Zhang, B Yuan, T Wang… - Iscience, 2022 - cell.com
The suprachiasmatic nucleus (SCN) integrates light and systemic signals from peripheral
tissues to coordinate physiology and behavior daily rhythms. However, the contribution that …