An inhibitory brainstem input to dopamine neurons encodes nicotine aversion

C Liu, AJ Tose, JPH Verharen, Y Zhu, LW Tang… - Neuron, 2022 - cell.com
Nicotine stimulates the dopamine (DA) system, which is essential for its rewarding effect.
Nicotine is also aversive at high doses; yet, our knowledge about nicotine's dose-dependent …

Neuronal nicotinic acetylcholine receptors are important targets for alcohol reward and dependence

J Wu, M Gao, DH Taylor - Acta Pharmacologica Sinica, 2014 - nature.com
Neuronal nicotinic acetylcholine receptors are important targets for alcohol reward and
dependence. Alcoholism is a serious public health problem and has been identified as the …

α6 subunit‐containing nicotinic receptors mediate low‐dose ethanol effects on ventral tegmental area neurons and ethanol reward

SC Steffensen, SI Shin, AC Nelson… - Addiction …, 2018 - Wiley Online Library
Dopamine (DA) neuron excitability is regulated by inhibitory GABAergic synaptic
transmission and modulated by nicotinic acetylcholine receptors (nAChRs). The aim of this …

Understanding the role α7 nicotinic receptors play in dopamine efflux in nucleus accumbens

R Maex, VP Grinevich, V Grinevich… - ACS chemical …, 2014 - ACS Publications
Neuronal nicotinic acetylcholine receptors (NNRs) of the α7 subtype have been shown to
contribute to the release of dopamine in the nucleus accumbens. The site of action and the …

Dopaminergic neurons in the ventral tegmental area and their dysregulation in nicotine addiction

G Dumont, R Maex, B Gutkin - Computational Psychiatry, 2018 - Elsevier
Nicotine is widely considered the major addictive substance in tobacco. While the receptor
mechanisms of nicotine have been identified, the circuit level mechanisms by which it …

[引用][C] Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors

ND Schilaty, DM Hedges, EY Jang, RJ Folsom… - … of Pharmacology and …, 2014 - ASPET

[图书][B] Alcohol Modulation of Dopamine Release

ND Schilaty - 2014 - search.proquest.com
The mesolimbic dopamine (DA) system projects from the ventral tegmental area (VTA) to
structures associated with the limbic system, primarily the nucleus accumbens (NAc). This …

[引用][C] Understanding the role 7 nicotinic receptors play in dopamine efflux in nucleus accumbens

R Maex, V Grinevich, V Grinevich, E Budygin…