The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Since the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights
have been gained into virus biology and the host factors that modulate the human immune …

Since the arrival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
December 2019, its characterization as a novel human pathogen, and the resulting …

Abstract Background Coronavirus disease 2019 (COVID-19) exhibits a wide spectrum of
clinical manifestations, ranging from asymptomatic to critical conditions. Understanding the …

Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune
host defense and immunoregulation. Considering the predisposition to develop severe and …

COVID-19 manifestations range from asymptomatic to life-threatening infections. The
outcome in different inborn errors of immunity (IEI) is still a matter of debate. In this …

The risk of severe adult respiratory coronavirus-2 (SARS-CoV-2) infection and the course of
the infection among individuals with common variable immunodeficiency (CVID) relative to …

The clinical evolution of patients infected with the Severe Acute Respiratory Coronavirus
type 2 (SARS-CoV-2) depends on the complex interplay between viral and host factors. The …

Primary immunodeficiencies (PIDs) are heterogeneous, rare disorders that increase
susceptibility to infection and/or immune dysregulation. Individuals with certain PIDs are at …

During the last three years, since the emergence of the COVID-19 pandemic, a significant
number of scientific publications have focused on resolving susceptibility to the infection, as …