[HTML][HTML] Luteolin, a flavonoid, as an anticancer agent: A review

M Imran, A Rauf, T Abu-Izneid, M Nadeem… - Biomedicine & …, 2019 - Elsevier
Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-
cancer compounds. Luteolin (3, 4, 5, 7-tetrahydroxy flavone) is a flavonoid found in different …

Luteolin as a modulator of skin aging and inflammation

F Gendrisch, PR Esser, CM Schempp, U Wölfle - Biofactors, 2021 - Wiley Online Library
Luteolin belongs to the group of flavonoids and can be found in flowers, herbs, vegetables
and spices. It plays an important role in defending plants, for example against UV radiation …

Plant flavonoids in cancer chemoprevention: role in genome stability

VC George, G Dellaire, HPV Rupasinghe - The Journal of nutritional …, 2017 - Elsevier
Carcinogenesis is a multistage process that involves a series of events comprising of
genetic and epigenetic changes leading to the initiation, promotion and progression of …

Molecular mechanisms of flavonoids in melanin synthesis and the potential for the prevention and treatment of melanoma

F Liu‐Smith, FL Meyskens - Molecular nutrition & food research, 2016 - Wiley Online Library
Flavonoids are becoming popular nutraceuticals. Different flavonoids show similar or distinct
biological effects on different tissues or cell types, which may limit or define their usefulness …

[HTML][HTML] Antagonistic efficacy of luteolin against lead acetate exposure-associated with hepatotoxicity is mediated via antioxidant, anti-inflammatory, and anti-apoptotic …

WA Al-Megrin, AF Alkhuriji, AOS Yousef, DM Metwally… - Antioxidants, 2019 - mdpi.com
The abundant use of lead (Pb; toxic heavy metal) worldwide has increased occupational
and ecosystem exposure, with subsequent negative health effects. The flavonoid luteolin …

Skin cancer, including related pathways and therapy and the role of luteolin derivatives as potential therapeutics

AM Juszczak, U Wöelfle, MZ Končić… - Medicinal research …, 2022 - Wiley Online Library
Cutaneous malignant melanoma is the fastest growing and the most aggressive form of skin
cancer that is diagnosed. However, its incidence is relatively scarce compared to the highest …

[HTML][HTML] Plant flavonoids on oxidative stress-mediated kidney inflammation

S Alsawaf, F Alnuaimi, S Afzal, RM Thomas… - Biology, 2022 - mdpi.com
Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …

Luteolin-loaded phytosomes sensitize human breast carcinoma MDA-MB 231 cells to doxorubicin by suppressing Nrf2 mediated signalling

M Sabzichi, H Hamishehkar, F Ramezani… - Asian Pacific Journal …, 2014 - koreascience.kr
Nuclear factor erythroid 2-related factor 2 (Nrf2) has been recognized as a transcription
factor that controls mechanisms of cellular defense response by regulation of three classes …

[HTML][HTML] Chemical structure, sources and role of bioactive flavonoids in cancer prevention: a review

G Drețcanu, I Știrbu, N Leoplold, D Cruceriu… - Plants, 2022 - mdpi.com
There has been a major shift in the collective mindset around the world in recent decades,
both in terms of food and in terms of the treatment of chronic diseases. Increasing numbers …

Delivery luteolin with folacin-modified nanoparticle for glioma therapy

C Wu, Q Xu, X Chen, J Liu - International Journal of Nanomedicine, 2019 - Taylor & Francis
Background Glioblastoma mutliforme is the most common and has the poorest prognosis of
any malignant tumor of the central nervous system. Luteolin, the most abundant xanthone …