[HTML][HTML] Serrated colorectal cancer: Preclinical models and molecular pathways

A Aiderus, N Barker, V Tergaonkar - Trends in Cancer, 2024 - cell.com
Serrated lesions are histologically heterogeneous, and detection can be challenging as
these lesions have subtle features that may be missed by endoscopy. Furthermore, while …

[HTML][HTML] SCFAs switch stem cell fate through HDAC inhibition to improve barrier integrity in 3D intestinal organoids from patients with obesity

M Farhadipour, K Arnauts, M Clarysse, T Thijs, K Liszt… - Iscience, 2023 - cell.com
Stem cells are a keystone of intestinal homeostasis, but their function could be shifted during
energy imbalance or by crosstalk with microbial metabolites in the stem cell niche. This …

[HTML][HTML] High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer

G Topi, SR Satapathy, S Ghatak, K Hellman… - Cell Communication and …, 2024 - Springer
In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …