Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases

JF Li, YT Dai, H Lilljebjörn, SH Shen… - Proceedings of the …, 2018 - National Acad Sciences
Most B cell precursor acute lymphoblastic leukemia (BCP ALL) can be classified into known
major genetic subtypes, while a substantial proportion of BCP ALL remains poorly …

The Ecoresponsive Genome of Daphnia pulex

JK Colbourne, ME Pfrender, D Gilbert, WK Thomas… - Science, 2011 - science.org
We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200
megabases and contains at least 30,907 genes. The high gene count is a consequence of …

How studies in developmental epithelial-mesenchymal transition and mesenchymal-epithelial transition inspired new research paradigms in biomedicine

JP Thiery, G Sheng, X Shu, R Runyan - Development, 2024 - journals.biologists.com
Epithelial-mesenchymal transition (EMT) and its reverse mechanism, mesenchymal-
epithelial transition (MET), are evolutionarily conserved mechanisms initially identified in …

KLF/SP transcription factor family evolution: expansion, diversification, and innovation in eukaryotes

JS Presnell, CE Schnitzler… - Genome biology and …, 2015 - academic.oup.com
The Krüppel-like factor and specificity protein (KLF/SP) genes play key roles in critical
biological processes including stem cell maintenance, cell proliferation, embryonic …

Global analysis of Drosophila Cys2-His2 zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants

MS Enuameh, Y Asriyan, A Richards… - Genome …, 2013 - genome.cshlp.org
Cys2-His2 zinc finger proteins (ZFPs) are the largest group of transcription factors in higher
metazoans. A complete characterization of these ZFPs and their associated target …

A new family of predicted Krüppel-like factor genes and pseudogenes in placental mammals

J Pei, NV Grishin - PloS one, 2013 - journals.plos.org
Krüppel-like factors (KLF) and specificity proteins (SP) constitute a family of zinc-finger-
containing transcription factors that play important roles in a wide range of processes …

Functional characterization of four metallothionein genes in Daphnia pulex exposed to environmental stressors

J Asselman, SP Glaholt, Z Smith, G Smagghe… - Aquatic toxicology, 2012 - Elsevier
We characterized the metallothionein genes (Mt1, Mt2, Mt3, and Mt4) in Daphnia pulex on
both molecular and ecotoxicological level. We therefore conducted a bioinformatical …

A study on the distribution of 37 well conserved families of C2H2 zinc finger genes in eukaryotes

A Seetharam, GW Stuart - Bmc Genomics, 2013 - Springer
Abstract Background The C2H2 zinc-finger (ZNF) containing gene family is one of the
largest and most complex gene families in metazoan genomes. These genes are known to …

C2H2 zinc finger proteins of the SP/KLF, Wilms tumor, EGR, Huckebein, and Klumpfuss families in metazoans and beyond

J Pei, NV Grishin - Gene, 2015 - Elsevier
Abstract Specificity proteins (SPs) and Krüppel-Like Factors (KLFs) are C2H2-type zinc
finger transcription factors that play essential roles in differentiation, development …

Extracellular vesicles and post-translational protein deimination signatures in haemolymph of the American lobster (Homarus americanus)

TJ Bowden, I Kraev, S Lange - Fish & Shellfish Immunology, 2020 - Elsevier
Abstract The American lobster (Homarus americanus) is a commercially important
crustacean with an unusual long life span up to 100 years and a comparative animal model …