[HTML][HTML] Eicosanoids in inflammation in the blood and the vessel

A Yamaguchi, E Botta, M Holinstat - Frontiers in pharmacology, 2022 - frontiersin.org
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids
in cells. PUFAs regulate cellular function through the formation of derived lipid mediators …

Neutrophil chemotaxis

B Petri, MJ Sanz - Cell and tissue research, 2018 - Springer
Neutrophils are the primary cells recruited to inflamed sites during an innate immune
response to tissue damage and/or infection. They are finely sensitive to inciting stimuli to …

Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease

JZ Haeggstrom, CD Funk - Chemical reviews, 2011 - ACS Publications
Metabolism of arachidonic acid leads to several families of lipid mediators, including
prostaglandins, thromboxane, leukotrienes, and lipoxins, along two major metabolic …

Prostaglandins and leukotrienes: advances in eicosanoid biology

CD Funk - science, 2001 - science.org
Prostaglandins and leukotrienes are potent eicosanoid lipid mediators derived from
phospholipase-released arachidonic acid that are involved in numerous homeostatic …

[图书][B] Wintrobe's clinical hematology

MM Wintrobe - 2009 - books.google.com
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology

H Harizi, JB Corcuff, N Gualde - Trends in molecular medicine, 2008 - cell.com
Arachidonic acid (AA)-derived eicosanoids belong to a complex family of lipid mediators that
regulate a wide variety of physiological responses and pathological processes. They are …

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

H Hirai, K Tanaka, O Yoshie, K Ogawa… - The Journal of …, 2001 - rupress.org
Prostaglandin (PG) D2, which has long been implicated in allergic diseases, is currently
considered to elicit its biological actions through the DP receptor (DP). Involvement of DP in …

Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation

T Shimizu - Annual review of pharmacology and toxicology, 2009 - annualreviews.org
Prostaglandins, leukotrienes, platelet-activating factor, lysophosphatidic acid, sphingosine 1-
phosphate, and endocannabinoids, collectively referred to as lipid mediators, play pivotal …

Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation

M Arita, T Ohira, YP Sun, S Elangovan… - The Journal of …, 2007 - journals.aai.org
Abstract Resolvin E1 (RvE1) is a potent anti-inflammatory and proresolving mediator derived
from omega-3 eicosapentaenoic acid generated during the resolution phase of …

Mediators of chronic obstructive pulmonary disease

PJ Barnes - Pharmacological reviews, 2004 - ASPET
Chronic obstructive pulmonary disease (COPD) is a major and increasing global health
problem that is now a leading cause of death. COPD is associated with a chronic …