The leading cause of several degenerative diseases such as atherosclerosis, cancer, aging,
cardiovascular, and inflammatory diseases is oxidative stress, a consequence of …

In the context of the new life-threatening COVID-19 pandemic caused by the SARS-CoV-2
virus, finding new antiviral and antimicrobial compounds is a priority in current research …

Heterocyclic compounds play a critical role in medicinal chemistry, and many available
drugs contain heterocyclic rings. A six-membered heterocyclic compound, pyridine, showed …

Hydrazones are a special class of organic compounds in the Schiff base family. Hydrazones
constitute a versatile compound of organic class having basic structure (R1R2C= NNR3R4) …

During HIV-1 genome replication, the viral reverse transcriptase-associated ribonuclease H
(RT-associated RNase H) activity hydrolyzes the RNA strand of RNA/DNA heteroduplex …

Three series of 6-aryl-2-methylnicotinohydrazides 4a–i, N′-arylidene-6-(4-bromophenyl)-2-
methylnicotino hydrazides 7a–f, and N′-(un/substituted 2-oxoindolin-3-ylidene)-6-(4 …

Abstract The FT-IR and FT-Raman spectra of N, N-Diethylnicotinamide (ENA), Nicotinic
Hydrazide (NHD) and 2-Mercaptonicotinic acid (MNA) were recorded and analyzed …

Reverse transcriptase (RT) plays an indispensable role in the replication of human
immunodeficiency virus (HIV) through its associated polymerase and ribonuclease H …

Background The purpose of this research is to illustrate the synthesis, characterization, and
reactivity of three new mononuclear complexes (NiSniL, CuSniL, and VOSniL) from the …

There is an urgent need to develop new antibacterial agents because of multidrug
resistance by bacteria and fungi. Schiff bases (aldehyde or ketone-like compounds) exhibit …