A personalized pharmaco-epistatic network model of precision medicine
L Feng, W Yang, M Ding, L Hou, C Gragnoli, C Griffin… - Drug discovery today, 2023 - Elsevier
Highlights•Functional graph (FunGraph) theory emerges to map pharmacogenetic
architecture.•The core tenet of FunGraph is to combine functional mapping and evolutionary …
architecture.•The core tenet of FunGraph is to combine functional mapping and evolutionary …
[HTML][HTML] NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity
J Moecking, P Laohamonthonkul, K Chalker… - Journal of Allergy and …, 2021 - Elsevier
Background NLRP1 is an innate immune sensor that can form cytoplasmic inflammasome
complexes. Polymorphisms in NLRP1 are linked to asthma; however, there is currently no …
complexes. Polymorphisms in NLRP1 are linked to asthma; however, there is currently no …
[PDF][PDF] “Redlining” to “Hot Spots”: The Impacts of a Continued Legacy of Structural and Institutional Racism and Bias on Asthma in Children
27 28 29 30 31 32 Conflict of Interest Disclosure: Dr. Jones receives support from the
National Institutes of 33 Health ((1R01HD100545 PI Jones; 2UG1OD024943 co-PI Jones; …
National Institutes of 33 Health ((1R01HD100545 PI Jones; 2UG1OD024943 co-PI Jones; …
[图书][B] Quantitative Methods for Precision Medicine: Pharmacogenomics in Action
R Wu - 2022 - taylorfrancis.com
Modern medicine is undergoing a paradigm shift from a" one-size-fits-all" strategy to a more
precise patient-customized therapy and medication plan. While the success of precision …
precise patient-customized therapy and medication plan. While the success of precision …
Role of Genetic Interactions in Lung Diseases Detection Using Computational Approaches: A Review
S Priya, R Manavalan - Current Chinese Computer Science, 2021 - benthamdirect.com
Genome-wide Association Studies (GWAS) give special insight into genetic differences and
environmental influences that are part of different human disorders and provide prognostic …
environmental influences that are part of different human disorders and provide prognostic …