Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

T Werfel, JP Allam, T Biedermann, K Eyerich… - Journal of allergy and …, 2016 - Elsevier
Atopic dermatitis (AD) is a complex skin disease frequently associated with other diseases of
the atopic diathesis. Recent evidence supports the concept that AD can also recognize other …

Immunology of atopic eczema: overcoming the T h1/T h2 paradigm

K Eyerich, N Novak - Allergy, 2013 - Wiley Online Library
Atopic eczema (AE) is a challenge for modern medicine, because it is prevalent, severely
affects quality of life of patients and their families, and causes high socioeconomic costs. The …

The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization

S Noda, M Suárez-Fariñas, B Ungar, SJ Kim… - Journal of Allergy and …, 2015 - Elsevier
Background Atopic dermatitis (AD) shows very high prevalence in Asia, with a large unmet
need for effective therapeutics. Direct comparisons between European American (EA) and …

[图书][B] Атопический дерматит у детей

ИИ Балаболкин, ВА Булгакова, ТИ Елисеева - 2018 - elibrary.ru
В издании обобщены исследования авторов и литературные данные по проблеме
атопического дерматита у детей. Представлены эпидемиология, этиология, патогенез …

Efficacy and safety of ustekinumab treatment in adults with moderate‐to‐severe atopic dermatitis

S Khattri, PM Brunner, S Garcet… - Experimental …, 2017 - Wiley Online Library
Atopic dermatitis (AD) is the most common inflammatory skin disease, but treatment options
for moderate‐to‐severe disease are limited. Ustekinumab is an IL‐12/IL‐23p40 antagonist …

Systemic treatment of adult atopic dermatitis: a review

M Megna, M Napolitano, C Patruno, A Villani… - Dermatology and …, 2017 - Springer
Atopic dermatitis (AD) is a common chronic inflammatory skin disease that predominantly
affects children. However, it can persist in adulthood and/or start at older ages. Due to its …

The evolving landscape of biologic therapies for atopic dermatitis: present and future perspective

E David, B Ungar, Y Renert‐Yuval… - Clinical & …, 2023 - Wiley Online Library
Atopic dermatitis (AD) is one of the most common, chronic inflammatory skin diseases with a
significant physical, emotional and socioeconomic burden. In recent years the …

EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders

O Boyman, C Kaegi, M Akdis, S Bavbek, A Bossios… - Allergy, 2015 - Wiley Online Library
Biologic agents (also termed biologicals or biologics) are therapeutics that are synthesized
by living organisms and directed against a specific determinant, for example, a cytokine or …

Biological therapies for atopic dermatitis: An update

D Deleanu, I Nedelea - Experimental and therapeutic …, 2019 - spandidos-publications.com
Severe atopic dermatitis, which affects both adults and children, is a debilitating disorder
with a significant decline of patients' quality of life. Although aetiopathogenic factors are …

Innate lymphoid cells: a new key player in atopic dermatitis

H Jia, H Wan, D Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Atopic dermatitis (AD) is a common allergic inflammatory skin condition mainly caused by
gene variants, immune disorders, and environmental risk factors. The T helper (Th) 2 …