Cell death mechanisms in stroke and novel molecular and cellular treatment options

E Sekerdag, I Solaroglu… - Current …, 2018 - ingentaconnect.com
As a result of ischemia or hemorrhage, blood supply to neurons is disrupted which
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …

Crosstalk between oxidative stress and ferroptosis/oxytosis in ischemic stroke: possible targets and molecular mechanisms

JX Ren, C Li, XL Yan, Y Qu, Y Yang… - Oxidative Medicine and …, 2021 - Wiley Online Library
Oxidative stress is a key cause of ischemic stroke and an initiator of neuronal dysfunction
and death, mainly through the overproduction of peroxides and the depletion of antioxidants …

Toxicity comparison of nano-sized and micron-sized microplastics to Goldfish Carassius auratus Larvae

H Yang, H Xiong, K Mi, W Xue, W Wei… - Journal of hazardous …, 2020 - Elsevier
Plastic pollution is one of the most serious environmental issues worldwide. The negative
influence of plastics on aquatic organisms has increasingly concerned, especially the …

Apoptosis and oxidative stress in neurodegenerative diseases

E Radi, P Formichi, C Battisti… - Journal of Alzheimer's …, 2014 - content.iospress.com
Neurodegenerative disorders affect almost 30 million individuals leading to disability and
death. These disorders are characterized by pathological changes in disease-specific areas …

Brain photobiomodulation therapy: a narrative review

F Salehpour, J Mahmoudi, F Kamari… - Molecular …, 2018 - Springer
Brain photobiomodulation (PBM) therapy using red to near-infrared (NIR) light is an
innovative treatment for a wide range of neurological and psychological conditions. Red/NIR …

Endoplasmic reticulum stress and the unfolded protein response in cerebral ischemia/reperfusion injury

L Wang, Y Liu, X Zhang, Y Ye, X Xiong… - Frontiers in Cellular …, 2022 - frontiersin.org
Ischemic stroke is an acute cerebrovascular disease characterized by sudden interruption of
blood flow in a certain part of the brain, leading to serious disability and death. At present …

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

Á Chamorro, U Dirnagl, X Urra, AM Planas - The Lancet Neurology, 2016 - thelancet.com
Treatments for acute ischaemic stroke continue to evolve after the superior value of
endovascular thrombectomy was confirmed over systemic thrombolysis. Unfortunately …

Lignans and their derivatives from plants as antivirals

Q Cui, R Du, M Liu, L Rong - Molecules, 2020 - mdpi.com
Lignans are widely produced by various plant species; they are a class of natural products
that share structural similarity. They usually contain a core scaffold that is formed by two or …

Therapeutic targets of oxidative/nitrosative stress and neuroinflammation in ischemic stroke: Applications for natural product efficacy with omics and systemic biology

H Chen, Y He, S Chen, S Qi, J Shen - Pharmacological Research, 2020 - Elsevier
Oxidative/nitrosative stress and neuroinflammation are critical pathological processes in
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …

A Bioinspired Manganese‐Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant …

J Wang, Y Wang, X Xiaohalati, Q Su, J Liu… - Advanced …, 2023 - Wiley Online Library
Following stroke, oxidative stress induced by reactive oxygen species (ROS) aggravates
neuronal damage and enlarges ischemic penumbra, which is devastating to stroke patients …