[HTML][HTML] Synthesis of novel star-shaped molecules based on a pentaerythritol core linked to different heterocyclic systems
Synthesis of analogs of known active compounds is the most often employed strategy for
producing important compounds. The Hantzsch reaction was employed to create new star …
producing important compounds. The Hantzsch reaction was employed to create new star …
Novel α-Cyano-Indolyl Chalcones as Anti-Cancer Candidates, Induce G1/S Cell Cycle Arrest and Sequentially Activate Caspases-7, 8, and 9 in Breast Carcinoma
AA Kashmiry, NS Ibrahim, MF Mohamed… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Six substituted α-cyano-indolylchalcones have been prepared and their structures were
verified by various spectral analysis tools. Compared with the standard drug 5-Fluorouracil) …
verified by various spectral analysis tools. Compared with the standard drug 5-Fluorouracil) …
Synthesis, antimicrobial, DNA binding, and computational studies of some bis-and poly (4-methyl-2H-chromen-2-one) derivatives
IMZ Fares, MA Ragheb, IA Abdelhamid… - Journal of Molecular …, 2025 - Elsevier
The research focused on studying how 7-hydroxy-4-methyl-2H-chromen-2-one can be used
as a building material for new bis-and poly (coumarins) through alkylation with related bis …
as a building material for new bis-and poly (coumarins) through alkylation with related bis …
New Halogenated Chalcones as Potential Anti-Inflammatory Agents: A Comprehensive In-Silico, In-Vitro, and In-Vivo Study with ADME Profiling
This study explored the anti-inflammatory potential of halogenated chalcone derivatives
using in-silico, in-vitro and in-vivo models. The synthesized compounds were assessed for …
using in-silico, in-vitro and in-vivo models. The synthesized compounds were assessed for …