Heart failure is a clinical syndrome where cardiac output is not sufficient to sustain adequate
perfusion and normal bodily functions, initially during exercise and in more severe forms …

A bioengineered construct that matches the chemical, mechanical, biological properties and
extracellular matrix morphology of native tissue could be suitable as a cardiac patch for …

Resulting from a various etiologies, the most notable remains ischemia; heart failure (HF)
manifests as the common end pathway of many cardiovascular processes and remains …

Biodegradable polyurethane patches have been applied as temporary mechanical supports
to positively alter the remodeling and functional loss following myocardial infarction. How …

Background To treat chronic heart failure (CHF), we developed a robust, easy to handle
bioabsorbable tissue-engineered patch embedded with human neonatal fibroblasts and …

Objective Myocardial infarction (MI) can lead to irreversible adverse left ventricular
remodeling resulting in subsequent severe dysfunction. The objective of this study was to …

Vascularization of engineered or damaged tissues is essential to maintain cell viability and
proper tissue function. Revascularization of the left ventricle (LV) of the heart after …

Coating of various synthetic, absorbable, and biologic meshes with mesenchymal stem cells
(MSCs) and fibroblasts was analyzed qualitatively and quantitatively. Five hernia meshes …

There are nearly 65 million people with chronic heart failure (CHF) globally, with no
treatment directed at the pathologic cause of the disease, the loss of functioning …

Background Varying strategies are currently being evaluated to develop tissue-engineered
constructs for the treatment of ischemic heart disease. This study examines an angiogenic …