Cytokines activate or inhibit immune cell behavior and are thus integral to all immune
responses. IL-1α and IL-1β are powerful apical cytokines that instigate multiple downstream …

Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the
destruction of tooth-supporting structures, being the presence of periodontopathogens …

Most breast cancers exhibit low immune infiltration and are unresponsive to immunotherapy.
We hypothesized that inhibition of the receptor activator of nuclear factor-κB (RANK) …

Eicosanoids are lipid-based signaling molecules that play a unique role in innate immune
responses. The multiple types of eicosanoids, such as prostaglandins (PGs) and …

Objective To determine the impact of endometriotic lesion removal on local and systemic
inflammation. Design Multiplex cytokine analysis on samples from endometriosis patients …

Background and purpose: Chemokines orchestrate neutrophil recruitment to inflammatory
foci. In the present study, we evaluated the participation of three chemokines, KC/CXCL1 …

Mast cells contribute to the pathogenesis of experimental autoimmune encephalomyelitis, a
rodent model of the human demyelinating disease multiple sclerosis. Yet their site and mode …

Aromatic essential oils play a significant role in pharmaceuticals, food additives, cosmetics,
and perfumery. Essential oils mostly comprise aliphatic hydrocarbons, monoterpenoids …

Abstract Purpose of Review The role of alveolar macrophages in innate immune responses
has long been appreciated. Here, we review recent studies evaluating the participation of …

Mast cells are tissue-resident cells best known for their role in allergy and host defence
against helminth parasites. They are involved in responses against other pathogenic …