Monitoring the microcirculation

D De Backer, K Donadello, DO Cortes - Journal of clinical monitoring and …, 2012 - Springer
One of the main goals of hemodynamic support is to preserve tissue perfusion. However
issue perfusion is related more to microvascular perfusion than aortic blood flow. Monitoring …

How to evaluate the microcirculation: report of a round table conference

D De Backer, S Hollenberg, C Boerma, P Goedhart… - Critical care, 2007 - Springer
Introduction Microvascular alterations may play an important role in the development of
organ failure in critically ill patients and especially in sepsis. Recent advances in technology …

Orthogonal polarization spectral imaging: a new method for study of the microcirculation

W Groner, JW Winkelman, AG Harris, C Ince… - Nature medicine, 1999 - nature.com
NEW TECHNOLOGY and its optical schematic are shown in Fig. 1a and b. To form the
image, the light is collected, passed through a spectral filter to isolate the wavelength region …

Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo

FM Klenke, Y Liu, H Yuan, EB Hunziker… - … Research Part A: An …, 2008 - Wiley Online Library
The repair of bone defects with biomaterials depends on a sufficient vascularization of the
implantation site. We analyzed the effect of pore size on the vascularization and …

Evaluation of sublingual and gut mucosal microcirculation in sepsis: a quantitative analysis

CL Verdant, D De Backer, A Bruhn… - Critical care …, 2009 - journals.lww.com
Objective: To determine the relationship between sublingual and intestinal mucosal
microcirculatory perfusion. Design: Observational, experimental study. Setting: University …

Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis

JGG Dobbe, GJ Streekstra, B Atasever… - Medical & biological …, 2008 - Springer
This study describes a new method for analyzing microcirculatory videos. It introduces
algorithms for quantitative assessment of vessel length, diameter, the functional …

Effective method for drug injection into subcutaneous tissue

H Kim, H Park, SJ Lee - Scientific reports, 2017 - nature.com
Subcutaneous injection of drug solution is widely used for continuous and low dose drug
treatment. Although the drug injections have been administered for a long time, challenges …

[PDF][PDF] VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo

E Wernike, MO Montjovent, Y Liu, D Wismeijer… - Eur Cell Mater, 2010 - dare.uva.nl
Bone formation and osseointegration of biomaterials are dependent on angiogenesis and
vascularization. Angiogenic growth factors such as vascular endothelial growth factor …

Neovascularization of poly(ether ester) block‐copolymer scaffolds in vivo: Long‐term investigations using intravital fluorescent microscopy

D Druecke, S Langer, E Lamme… - … Research Part A: An …, 2004 - Wiley Online Library
Poly (ether ester) block‐copolymer scaffolds of different pore size were implanted into the
dorsal skinfold chamber of balb/c mice. Using intravital fluorescent microscopy, the temporal …

Influence of the application of platelet‐enriched plasma in oral mucosal wound healing

JAH Lindeboom, KR Mathura… - Clinical oral implants …, 2007 - Wiley Online Library
Purpose: The aim of this study was to describe and quantify the therapeutic value of platelet
concentrate on the capillary density in oral mucosal wound healing. Material and methods …