[HTML][HTML] Does the food processing contaminant acrylamide cause developmental neurotoxicity? A review and identification of knowledge gaps

B Lindeman, Y Johansson, M Andreassen… - Reproductive …, 2021 - Elsevier
There is a worldwide concern on adverse health effects of dietary exposure to acrylamide
(AA) due to its presence in commonly consumed foods. AA is formed when carbohydrate …

Neuroprotective effects of thymoquinone in acrylamide-induced peripheral nervous system toxicity through MAPKinase and apoptosis pathways in rat

J Tabeshpour, S Mehri, K Abnous… - Neurochemical …, 2019 - Springer
Acrylamide (ACR) is extensively used in industrial areas and has been demonstrated to
induce neurotoxicity via oxidative stress and apoptosis. In this study, we assessed the …

Acrylamide impairs ovarian function by promoting apoptosis and affecting reproductive hormone release, steroidogenesis and autophagy-related genes: An in vivo …

N Aldawood, A Alrezaki, S Alanazi, N Amor… - Ecotoxicology and …, 2020 - Elsevier
Acrylamide (ACR) toxicity is quite common due to its widespread use in industry and due to
the Maillard browning reaction that occurs in foods containing high concentrations of …

Modelling acrylamide acute neurotoxicity in zebrafish larvae

E Prats, C Gómez-Canela, S Ben-Lulu, T Ziv… - Scientific reports, 2017 - nature.com
Abstract Acrylamide (ACR), a type-2 alkene, may lead to a synaptopathy characterized by
ataxia, skeletal muscles weakness and numbness of the extremities in exposed human and …

Spontaneous officinal plants in the Cilento, Vallo di Diano and Alburni National Park: Tradition, protection, enhancement, and recovery

E De Falco, D Rigano, V Fico, A Vitti, G Barile… - Plants, 2023 - mdpi.com
The aim of this study was to deepen our knowledge on the heritage and traditional uses of
some medicinal plants of the Cilento, Vallo di Diano and Alburni National Park (Salerno …

Cerium oxide nanoparticles protects against acrylamide induced toxicity in HepG2 cells through modulation of oxidative stress

A Azari, M Shokrzadeh, E Zamani… - Drug and Chemical …, 2019 - Taylor & Francis
Acrylamide (AA) is a toxic chemical compound found in cooked foods. Considerable
evidences suggest that oxidative stress and mitochondrial dysfunction are contributed to AA …

Acrylamide, applied during pregnancy and postpartum period in offspring rats, significantly disrupted myelination by decreasing the levels of myelin-related proteins …

MM Üremiş, N Üremiş, M Gül, S Gül, Y Çiğremiş… - Neurochemical …, 2024 - Springer
Acrylamide (ACR) is a colorless, odorless, and water-soluble solid molecule. In addition to
being an important industrial material, ACR is found in fried and baked carbohydrate-rich …

Effect of acrylamide-induced neurotoxicity in a primary astrocytes/microglial co-culture model

M Zhao, FSL Wang, XS Hu, F Chen, HM Chan - Toxicology in Vitro, 2017 - Elsevier
Acrylamide (AA), is a common food contaminant generated by heat processing. Astrocytes
and microglia are the two major glial cell types in the brain that play pivotal but different roles …

Learning, memory deficits, and impaired neuronal maturation attributed to acrylamide

S Lee, HR Park, JY Lee, JH Cho, HM Song… - Journal of Toxicology …, 2018 - Taylor & Francis
Acrylamide (ACR) is a neurotoxin known to produce neurotoxicity characterized by ataxia,
skeletal muscle weakness, cognitive impairment, and numbness of the extremities …

Metformin protects against experimental acrylamide neuropathy in rats

SS Oda - Drug development research, 2017 - Wiley Online Library
ABSTRACT Preclinical Research To investigate the potential neuroprotective effects of
metformin against experimental acrylamide neuropathy in rats, 24 rats were distributed into …