The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and
medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its …

Objective An association between bipolar disorder and cognitive impairment has repeatedly
been described, even for euthymic patients. Findings are inconsistent both across primary …

Fronto-limbic white matter (WM) abnormalities are assumed to lie at the heart of the
pathophysiology of bipolar disorder (BD); however, diffusion tensor imaging (DTI) studies …

Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …

Identifying both the commonalities and differences in brain structures among psychiatric
disorders is important for understanding the pathophysiology. Recently, the ENIGMA …

In this review paper we address whether deficits in reading (ie developmental dyslexia) are
rooted in neurobiological anomalies in white matter tracts. Diffusion tensor imaging (DTI) …

From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …

Objectives In the coming generation, older adults with bipolar disorder (BD) will increase in
absolute numbers as well as proportion of the general population. This is the first report of …

This work provides an overview of the most consistent alterations in bipolar disorder (BD),
attempting to unify them in an internally coherent working model of the pathophysiology of …